Evidence map›Paper›PMID 36860465›Full record

ArticleAquaculture nutrition2022

The Effects of Dietary Thyme Oil (Thymus vulgaris) Essential Oils for Common Carp (Cyprinus carpio): Growth Performance, Digestive Enzyme Activity, Antioxidant Defense, Tissue and Mucus Immune Parameters, and Resistance against Aeromonas hydrophila.

Hamed Ghafarifarsani, Seyed Hossein Hoseinifar, Atefeh Sheikhlar, Mehdi Raissy, Fatemeh Heidarinezhad Chaharmahali, Worawit Maneepitaksanti, Mehwish Faheem, Hien Van Doan

Open access · goldAbstract read
In one paragraph

Article in Aquaculture nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Dietary Combined Thyme Meal andVeterinary sciences · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Effects of Ivy (Aquaculture nutrition · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Hamed GhafarifarsaniDepartment of Fisheries, Faculty of Natural Resources, Urmia University, Urmia, Iran.ORCID https://orcid.org/0000-0003-1199-6109
Seyed Hossein HoseinifarDepartment of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.ORCID https://orcid.org/0000-0002-0210-9013
Atefeh SheikhlarAnimal Science Department, Van Hall Larenstein University-Wageningen University and Research, Netherlands.ORCID https://orcid.org/0000-0001-8219-4846
Mehdi RaissyDepartment of Aquatic Animal Health, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.ORCID https://orcid.org/0000-0001-6979-3916
Fatemeh Heidarinezhad ChaharmahaliFaculty of Basic Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.ORCID https://orcid.org/0000-0001-7745-8472
Worawit ManeepitaksantiDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai, Thailand.ORCID https://orcid.org/0000-0001-6777-2468
Mehwish FaheemDepartment of Zoology, Government College University, Lahore 54000, Pakistan.ORCID https://orcid.org/0000-0002-7508-8196
Hien Van DoanDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai, Thailand.ORCID https://orcid.org/0000-0002-7299-7087
Chiang Mai University · THIslamic Azad University of Shahrekord · IRGorgan University of Agricultural Sciences and Natural Resources · IRGovernment College University, Lahore · PKUrmia University · IRVan Hall Larenstein University of Applied Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of dietary supplementation of thyme (Thymus vulgaris) essential oil (TVO) on growth performance, digestive enzymes, biochemical parameters, hematological indices, liver enzymes, and pathogen resistance in common carp (Cyprinus carpio). Triplicate groups of fish (15.36 ± 0.10 g) were fed daily with diets supplemented with TVO at 0, 0.5, 1, and 2 percent for 60 days then challenged with Aeromonas hydrophila. The results determined that supplementation of thyme resulted in significantly higher final body weights (FBW) and lower feed conversion ratios (FCR). Furthermore, no mortality was observed in the thyme-supplemented treatments. Regression analysis showed that fish growth parameters were polynomially related to dietary TVO levels. The optimum dietary TVO level, based upon the varied growth parameters, was 1.344 to 1.436%. Digestive enzymes activity, including amylase and protease, significantly increased in fish fed the supplemented diets. The thyme-supplemented diets also significantly increased the biochemical parameters, including total protein, albumin, and acid phosphatase (ACP), compared to the control group. We also observed significant increases in hematological indices, including red blood cells (RBC), white blood cells (WBC), hematocrit (Hct), and hemoglobin (Hb) in common carp fed diets containing thyme oil (

Identifiers

PMID36860465
PMCPMC9973159
OpenAlexW4296131649

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.