ArticleAquaculture nutrition2022
Dietary Leucine Supplementation Improves Muscle Fiber Growth and Development by Activating AMPK/Sirt1 Pathway in Blunt Snout Bream (
Article in Aquaculture nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Bioactives and exercise synergize to modulate AMPK and inflammation.Frontiers in immunology · 2025Pooled it
- Effects of Dietary Leucine Levels on Growth Performance and Muscle Quality in Oriental River Prawn (Biology · 2026Article
- Gene Expression-Based Classification of European Seabass Larval Batches According to Saddleback Syndrome Incidence Using Machine Learning.Animals : an open access journal from MDPI · 2026Article
- PPARα-CD36-CAV1-mediated docosahexaenoic acid (DHA) uptake promotes muscle fiber development in grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- In Vitro Fish Cell Culture: From Primary Muscle Cells to Cell-Based Meat in Cyprinidae.Biology · 2026Review
- Effects of Jack Mackerel Meal Inclusion in Diets Replacing Fish Meal With Combined Tuna By-Product and Corn Gluten Meals on the Growth and Feed Utilization of Red Sea Bream (Aquaculture nutrition · 2026Article
- Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study.Experimental and therapeutic medicine · 2026Article
- Glycerophospholipid fatty acid remodeling optimizes lipid nutrition and volatile organic compound composition in freshwater fish with linolenic acid intervention.Food chemistry: X · 2025Article
- Optimizing Muscle Quality in Common Carp (Foods (Basel, Switzerland) · 2025Article
- Influences of Diet Quality, Nursery-Habitat Complexity and Sex on Brain Development and Cognitive Performance of Brown Trout (Ecology and evolution · 2025Article
- Effects of Dietary Docosahexaenoic Acid Levels on the Growth, Body Composition, and Health of Liver and Intestine in Juvenile Tiger Puffer (Animals : an open access journal from MDPI · 2025Article
- Dietary supplementation with glutamate improves the flesh quality of gibel carp (Journal of nutritional science · 2025Article
- Omega-3 fatty acids: multi-target mechanisms and therapeutic applications in neurodevelopmental disorders and epilepsy.Frontiers in nutrition · 2025Review
- Transcriptomics and Metabolomics Explain the Crisping Mechanisms of Broad Bean-Based Crisping Diets on Nile Tilapia (Metabolites · 2024Article
- Effects of Different Astaxanthin Sources on Fillet Coloration and Energy Deposition in Rainbow Trout (Aquaculture nutrition · 2024Article
- (-)-Epigallocatechin-3-O-Gallate Regulates Muscle Growth, Antioxidant Status, and Nutritional Composition of Juvenile Common Carp (Aquaculture nutrition · 2024Article
- Assessment of black soldier fly (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Improving flesh quality of grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Dietary DHA Enhanced the Textural Firmness of Common Carp (Foods (Basel, Switzerland) · 2022Article
- Effects of sheep slaughter age on myogenic characteristics in skeletal muscle satellite cells.Animal bioscience · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This research is aimed at evaluating the effects of leucine supplementation on muscle fibers growth and development of blunt snout bream through a feeding trial and a primary muscle cells treatment. An 8-week trial with diets containing 1.61% leucine (LL) or 2.15% leucine (HL) was conducted in blunt snout bream (mean initial weight = 56.56 ± 0.83 g). Results demonstrated that the specific gain rate and the condition factor of fish in the HL group were the highest. The essential amino acids content of fish fed HL diets was significantly higher than that fed LL diets. The texture (hardness, springiness, resilience, and chewiness), the small-sized fiber ratio, fibers density, and sarcomere lengths in fish all obtained the highest in the HL group. Additionally, the proteins expression related with the activation of the AMPK pathway (p-Ampk, Ampk, p-Ampk/Ampk, and Sirt1) and the expression of genes (myogenin (
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Registered trials
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