Evidence map›Paper›PMID 36859737›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Light- and drug-induced pupillary dynamics in eyes with a retropupillary iris-claw intraocular lens.

Carlo Bellucci, Andrea Perrella, Maurizio Rossi, Annalaura Papapicco, Federico Spadini, Salvatore Antonio Tedesco, Stefano Gandolfi, Paolo Mora

Open access · hybridAbstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Carlo BellucciOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Andrea PerrellaOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Maurizio RossiDepartment of Clinical and Experimental Medicine, University Hospital of Parma, Parma, Italy.
Annalaura PapapiccoOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Federico SpadiniOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Salvatore Antonio TedescoOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Stefano GandolfiOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Paolo MoraOphthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy. paolo.mora@unipr.it.ORCID http://orcid.org/0000-0001-7133-8250
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe evaluated the pupillary characteristics and response to light and drugs in eyes with posterior chamber (PC) placement of iris-claw intraocular lens (IC-IOL).

methodsIn this cross-sectional, comparative study, we included adults with an IC-IOL implanted in the PC of a single eye. We excluded patients with ocular trauma, postoperative IC-IOL displacement or complications, and extended iris atrophy. We used anterior segment optical coherence tomography to perform light-controlled pupillography, measure the pupil diameter (PD), and estimated the pupil circularity under mesopic conditions. PD was also assessed under photopic, scotopic, pharmacological mydriasis, and miosis conditions. The results were compared to those of the fellow eye, phakic, or regular pseudophakic.

resultsThe IC-IOL and control groups included 30 eyes each. The most frequent reasons for IC-IOL implantation were complicated cataract (37%) and dislocated/luxated prior IOL (33%). Compared to the control group, the IC-IOL group had lower visual acuity, a smaller PD under scotopic conditions (p = 0.0010) and after pharmacological mydriasis (p < 0.0001), and a larger PD after pharmacological miosis (p < 0.0001). Mesopic pupil circularity was comparable between the groups. We also considered ongoing extraocular treatments with possible effects on iris motility.

conclusionsThe pupillary size and profile were similar between the groups in mesopic light. Reduced mydriasis was noted in response to light and drugs, while the degree of miosis was reduced in response to inducing drugs in the IC-IOL compared to the control group. This study complements previous results concerning the PC placement of IC-IOLs by adding original observations on drug-induced pupil motility.

Indexed as

Lenses, IntraocularMydriasisAdultCross-Sectional StudiesHumansLens Implantation, IntraocularMiosisPupilCataract surgeryIris-claw IOLPharmacological miosisPharmacological mydriasisPupillary dynamics

Identifiers

PMID36859737
PMCPMC10368576
OpenAlexW4322758045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.