Evidence map›Paper›PMID 36859695›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2023

Characterization of polypropyleneimine as an alternative transfection reagent.

Riku Saeki, Shingo Kobayashi, Rena Shimazui, Teruki Nii, Akihiro Kishimura, Takeshi Mori, Masaru Tanaka, Yoshiki Katayama

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Biomacromolecules · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Riku Saeki *Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan.
Shingo Kobayashi *Soft Materials Chemistry, Institute for Materials Chemistry and Engineering, Kyushu University, Build. CE41, 744 Motooka, Nishi-Ku, Fukuoka, 819-0395, Japan.
Rena Shimazui *Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan.
Teruki NiiGraduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan.
Akihiro KishimuraGraduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan.
Takeshi MoriGraduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan. mori.takeshi.880@m.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0002-1821-5427
Masaru TanakaSoft Materials Chemistry, Institute for Materials Chemistry and Engineering, Kyushu University, Build. CE41, 744 Motooka, Nishi-Ku, Fukuoka, 819-0395, Japan. tanaka.masaru.763@m.kyushu-u.ac.jp.
Yoshiki KatayamaGraduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan. katayama.yoshiki.958@m.kyushu-u.ac.jp.
Kyushu University · JP

Funding

MEXT KAKENHI JP19H05720MEXT KAKENHI JP20H05876
6 · The paper itself

Abstract

Polypropyleneimine (PPI) was examined as a transfection reagent comparing with most widely used polymer, polyethyleneimine (PEI). PPI had better responsiveness to the endosomal pH and showed more condensation ability of plasmid DNA than PEI. Although the cytotoxicity of PPI was somewhat higher than PEI, the transfection efficacy of PPI was comparable with PEI or higher than PEI in some cell line. Thus, PPI would be an alternative transfection reagent.

Indexed as

PolyethyleneiminePolypropylenesCell LineIndicators and ReagentsPlasmidsTransfectionIndicators and ReagentsPolyethyleneiminepoly(propyleneimine)PolypropylenesPolypropyleneimineSynthetic vectorTransfection

Identifiers

PMID36859695
OpenAlexW4322732079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.