Evidence map›Paper›PMID 36859576›Full record

ArticleScientific reports2023

Subset of the periodontal ligament expressed leptin receptor contributes to part of hard tissue-forming cells.

Hirotsugu Oka, Shinichirou Ito, Mana Kawakami, Hodaka Sasaki, Shinichi Abe, Satoru Matsunaga, Sumiharu Morita, Taku Noguchi, Norio Kasahara, Akihide Tokuyama and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Stem-cell regulation in periodontium formation and regeneration.Journal of bone and mineral metabolism · 2026
    Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Hirotsugu Oka *Department of Oral and Maxillofacial Implantology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Shinichirou Ito *Department of Pharmacology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Mana KawakamiDepartment of Oral Pathobiological Science and Surgery, Tokyo Dental College, Tokyo, 101-0061, Japan.
Hodaka SasakiDepartment of Oral and Maxillofacial Implantology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Shinichi AbeDepartment of Anatomy, Tokyo Dental College, Tokyo, 101-0061, Japan.
Satoru MatsunagaDepartment of Anatomy, Tokyo Dental College, Tokyo, 101-0061, Japan.
Sumiharu MoritaDepartment of Anatomy, Tokyo Dental College, Tokyo, 101-0061, Japan.
Taku NoguchiDepartment of Anatomy, Tokyo Dental College, Tokyo, 101-0061, Japan.
Norio KasaharaDepartment of Histology and Developmental Biology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Akihide TokuyamaDepartment of Pharmacology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Masataka KasaharaDepartment of Pharmacology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Akira KatakuraDepartment of Oral Pathobiological Science and Surgery, Tokyo Dental College, Tokyo, 101-0061, Japan.
Yasutomo YajimaDepartment of Oral and Maxillofacial Implantology, Tokyo Dental College, Tokyo, 101-0061, Japan.
Toshihide MizoguchiOral Health Science Center, Tokyo Dental College, Tokyo, 101-0061, Japan. tmizoguchi@tdc.ac.jp.
Tokyo Dental College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lineage of periodontal ligament (PDL) stem cells contributes to alveolar bone (AB) and cementum formation, which are essential for tooth-jawbone attachment. Leptin receptor (LepR), a skeletal stem cell marker, is expressed in PDL; however, the stem cell capacity of LepR

Indexed as

Periodontal LigamentReceptors, LeptinCell DifferentiationConnective Tissue CellsStem CellsReceptors, Leptin

Identifiers

PMID36859576
PMCPMC9977939
OpenAlexW4322739079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.