Evidence map›Paper›PMID 36859562›Full record

SynthesisJournal of child psychology and psychiatry, and allied disciplines2023

Treatment of childhood disruptive behavior disorders and callous-unemotional traits: a systematic review and two multilevel meta-analyses.

Samantha Perlstein, Maddy Fair, Emily Hong, Rebecca Waller

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of child psychology and psychiatry, and allied disciplines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
29.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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  15. Annual Research Review: Early conduct problems - precursors, outcomes, and etiology.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samantha PerlsteinDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-6584-0786
Maddy FairDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Emily HongDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Rebecca WallerDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-5069-1183
University of Pennsylvania · US

Funding

Risky Parenting and Temperament Pathways To Callous-Unemotional Traits In Early ChildhoodR01MH125904 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Nicholas J Wagner, Rebecca Waller · 2022 to 2026
$3.9M
Leveraging Machine Learning Techniques to Elucidate Risk for Callous-Unemotional TraitsR21MH126162 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI WAGNER, NICHOLAS J, WALLER, REBECCA · 2022 to 2023
$450k
NIMH NIH HHS R01 MH125904NIMH NIH HHS R21 MH126162
6 · The paper itself

Abstract

backgroundChildren with callous-unemotional (CU) traits are at high lifetime risk of antisocial behavior. It is unknown if treatments for disruptive behavior disorders are as effective for children with CU traits (DBD+CU) as those without (DBD-only), nor if treatments directly reduce CU traits. Separate multilevel meta-analyses were conducted to compare treatment effects on DBD symptoms for DBD+CU versus DBD-only children and evaluate direct treatment-related reductions in CU traits, as well as to examine moderating factors for both questions.

methodsWe systematically searched PsycINFO, PubMed, Cochran Library (Trials), EMBASE, MEDLINE, APA PsycNet, Scopus, and Web of Science. Eligible studies were randomized controlled trials, controlled trials, and uncontrolled studies evaluating child-focused, parenting-focused, pharmacological, family-focused, or multimodal treatments.

resultsSixty studies with 9,405 participants were included (M

conclusionsDBD+CU children improve with treatment, but their greater DBD symptom severity requires specialized treatment modules that could be implemented alongside parenting programs. Conclusions are tempered by heterogeneity across studies and scant evidence from randomized controlled trials.

Indexed as

Conduct DisorderProblem BehaviorAttention Deficit and Disruptive Behavior DisordersChildChild, PreschoolEmotionsEthnicityFemaleHumansMaleMinority GroupsCallous-unemotional traitsdisruptive behaviorinterventionparentingtreatment

Identifiers

PMID36859562
PMCPMC10471785
OpenAlexW4322721805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.