Evidence map›Paper›PMID 36859556›Full record

ReviewThe Journal of the Egyptian Public Health Association2023

A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM).

Nermin A Osman, Mohammed Moustapha Anwar, Bivek Singh, Girish K Gupta, Amgad M Rabie

Open access · diamondAbstract readReview
In one paragraph

Review in The Journal of the Egyptian Public Health Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Nermin A OsmanBiomedical Informatics and Medical Statistics Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0001-7845-1854
Mohammed Moustapha AnwarDepartment of Biotechnology, Institute of Graduate Studies and Research (IGSR), Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0001-5035-8463
Bivek SinghTongji University, Shanghai, China.
Girish K GuptaDepartment of Pharmaceutical Chemistry, Sri Sai College of Pharmacy, Badhani, Pathankot, 145001, Punjab, India.
Amgad M RabieDrug Discovery & Clinical Research Department, Dikernis General Hospital (DGH), Magliss El-Madina Street, Dikernis City, 35744, Dikernis, Dakahlia Governorate, Egypt. amgadpharmacist1@yahoo.com.ORCID http://orcid.org/0000-0003-3681-114X
Alexandria University · EGAlkermes (Ireland) · IESri Sai University · INTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) is responsible for a high mortality rate due to its unique and severe host-pathogen interactions. Critically ill or immunocompromised COVID-19 patients are more prone to suffer from aggressive mycoses. Probable victims include those with uncontrolled diabetes mellitus (DM), metabolic acidosis, prolonged neutropenia, increased ferritin levels, hypoxia, and prolonged hospitalization with/without mechanical ventilators and corticosteroids administration. The current review aims to outline the journey of patients with CAM as well as the advantages and disadvantages of the currently available diagnostic techniques. It also discussed the current status of treatment options and caveats in the management of mucormycosis. Multidisciplinary team, early diagnosis, controlling the predisposing condition(s), complete surgical debridement, effective antifungal therapies (e.g., amphotericin B, isavuconazole, and posaconazole), and implementing antifungal stewardship programs are imperative in CAM cases.

Indexed as

Antifungal stewardshipAntifungal therapiesAntimicrobial resistanceCAMComplete surgical debridementCOVID-19MucormycosisMultidisciplinary team

Identifiers

PMID36859556
PMCPMC9977480
OpenAlexW4322722243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.