Evidence map›Paper›PMID 36859114›Full record

ArticleThe Journal of the Acoustical Society of America2023

Reconstruction of transverse-longitudinal vibrations in the organ of Corti complex via optical coherence tomography.

Brian L Frost, Clark Elliott Strimbu, Elizabeth S Olson

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Imaging theJournal of biomedical optics · 2025
    Article
  3. Article
  4. Article
  5. Corti Fluid Is a Medium for Outer Hair Cell Force Transmission.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brian L FrostDepartment of Electrical Engineering, Columbia University, 500 West 120th Street, Mudd 1310, New York, New York 10027, USA.
Clark Elliott StrimbuDepartment of Otolaryngology Head and Neck Surgery, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA.ORCID 0000-0001-6298-3709
Elizabeth S OlsonDepartment of Otolaryngology Head and Neck Surgery, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA.
Columbia University · US

Funding

Diversity Supplement to Auditory Mechanics and Cochlear AmplificationR01DC015362 · NIDCD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ELIZABETH S. OLSON · 2016 to 2026
$5.6M
Reconstruction of three-dimensional organ of Corti micromechanical motion patterns via optical coherence tomographyF31DC020621 · NIDCD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI FROST, BRIAN LANCE · 2022 to 2023
$79k
NIDCD NIH HHS F31 DC020621NIDCD NIH HHS R01 DC015362
6 · The paper itself

Abstract

Optical coherence tomography (OCT) is a common modality for measuring vibrations within the organ of Corti complex (OCC) in vivo. OCT's uniaxial nature leads to limitations that complicate the interpretation of data from cochlear mechanics experiments. The relationship between the optical axis (axis of motion measurement) and anatomically relevant axes in the cochlea varies across experiments, and generally is not known. This leads to characteristically different motion measurements taken from the same structure at different orientations. We present a method that can reconstruct two-dimensional (2-D) motion of intra-OCC structures in the cochlea's longitudinal-transverse plane. The method requires only a single, unmodified OCT system, and does not require any prior knowledge of precise structural locations or measurement angles. It uses the cochlea's traveling wave to register points between measurements taken at multiple viewing angles. We use this method to reconstruct 2-D motion at the outer hair cell/Deiters cell junction in the gerbil base, and show that reconstructed transverse motion resembles directly measured transverse motion, thus validating the method. The technique clarifies the interpretation of OCT measurements, enhancing their utility in probing the micromechanics of the cochlea.

Indexed as

Tomography, Optical CoherenceVibrationAnimalsCochleaGerbillinaeMotionOrgan of Corti

Identifiers

PMID36859114
PMCPMC9957605
OpenAlexW4321615139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.