Evidence map›Paper›PMID 36858826›Full record

ArticleeNeuro2023

Bicistronic Expression of a High-Performance Calcium Indicator and Opsin for All-Optical Stimulation and Imaging at Cellular Resolution.

Paul K LaFosse, Zhishang Zhou, Nina G Friedman, Yanting Deng, Anna J Li, Bradley Akitake, Mark H Histed

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Rapid rebalancing of co-tuned ensemble activity in the auditory cortex.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Cellular-resolution optogenetics reveals attenuation-by-suppression in visual cortical neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Reverse-engineering placebo analgesia.Current biology : CB · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 3 countries.

Paul K LaFosseIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Zhishang ZhouIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Nina G FriedmanIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Yanting DengIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0001-7582-6059
Anna J LiIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Bradley AkitakeIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Mark H HistedIntramural Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 mark.histed@nih.gov.ORCID 0000-0001-8235-7908
National Institutes of Health · US

Funding

Readout and control of spatiotemporal neuronal codes for behaviorU19NS107464 · NINDS · UNIVERSITY OF CHICAGO · PI SHOHAM, SHY · 2018 to 2022
$17.3M
Patterns of neuronal activity underlying behavioral decisionsZIAMH002956 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HISTED, MARK · 2016 to 2025
$11.1M
Computation by recurrent circuits of the cerebral cortexZIAMH002967 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HISTED, MARK · 2017 to 2025
$7.0M
BRAIN project (Histed): Readout and Control of Spatiotemporal Neuronal Codes of BehaviorZIAMH002972 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HISTED, MARK · 2019 to 2023
$1.5M
Intramural NIH HHS ZIA MH002967NINDS NIH HHS U19 NS107464
6 · The paper itself

Abstract

State-of-the-art all-optical systems promise unprecedented access to neural activity

Indexed as

CalciumOpsinsAnimalsMiceNeuronsOptogeneticsPhotic StimulationRod OpsinsCalciumOpsinsRod Opsins

Identifiers

PMID36858826
PMCPMC10062490
OpenAlexW4322757829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.