Evidence map›Paper›PMID 36858516›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Anti-myelin Oligodendrocyte Glycoprotein Antibody-positive Myelitis after Coronavirus Disease 2019.

Kenji Uchino, Kaima Soga, Kensuke Shinohara, Takeshi Imai, Iori Motohashi, Hirohisa Okuma, Yoshihisa Yamano

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kenji UchinoDepartment of Neurology, Kawasaki Municipal Tama Hospital, Japan.
Kaima SogaDepartment of Neurology, Kawasaki Municipal Tama Hospital, Japan.
Kensuke ShinoharaDepartment of Neurology, Kawasaki Municipal Tama Hospital, Japan.
Takeshi ImaiDepartment of Neurology, St. Marianna University School of Medicine, Japan.
Iori MotohashiDepartment of General Medical Care, Internal Medicine Unit, Kawasaki Municipal Tama Hospital, Japan.
Hirohisa OkumaDepartment of Neurology, Kawasaki Municipal Tama Hospital, Japan.
Yoshihisa YamanoDepartment of Neurology, St. Marianna University School of Medicine, Japan.
Kawasaki Municipal Hospital · JPSt. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of anti-myelin oligodendrocyte glycoprotein (MOG) antibody-related myelitis caused by coronavirus disease (COVID-19) infection in 2021. A 22-year-old man with no history of any related illness contracted COVID-19. Eight days later, he developed bladder problems, paraplegia and sensory disturbances. Cervical spinal cord magnetic resonance imaging revealed extensive hyperintensity at T2 and spinal cord lesions extending from C4 to Th1. The patient was diagnosed with transverse myelitis and started on intravenous methylprednisolone, plasma exchange and intravenous immunoglobulin therapy. The symptoms improved only after intravenous methylprednisolone therapy. Anti-MOG antibodies were found in his serum and cerebrospinal fluid during routine screening. As this observation is unusual and could cause serious health problems, we wonder if COVID-19 triggered this autoimmune response.

Indexed as

COVID-19MyelitisMyelitis, TransverseAutoantibodiesHumansMagnetic Resonance ImagingMaleMethylprednisoloneMyelin-Oligodendrocyte GlycoproteinOligodendrogliaAutoantibodiesMethylprednisoloneMyelin-Oligodendrocyte GlycoproteinautoimmuneCOVID-19oligodendrocyte myelin glycoproteinprednisolonetransverse myelitis

Identifiers

PMID36858516
PMCPMC10258110
OpenAlexW4322705821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.