Evidence map›Paper›PMID 36858476›Full record

ArticleBMJ open2023

Examining non-linearity in the association between age and reported opioid use in different socioeconomic strata: cohort study using Health Survey for England waves from 1997 to 2014.

Magdalena Nowakowska, Salwa S Zghebi, Li-Chia Chen, Darren M Ashcroft, Evangelos Kontopantelis

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

Magdalena NowakowskaNIHR School for Primary Care Research, The University of Manchester, Manchester, UK.ORCID 0000-0003-1386-2534
Salwa S ZghebiNIHR School for Primary Care Research, The University of Manchester, Manchester, UK.ORCID 0000-0002-7978-1094
Li-Chia ChenDivision of Pharmacy and Optometry; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Darren M AshcroftNIHR School for Primary Care Research, The University of Manchester, Manchester, UK.
Evangelos KontopantelisNIHR School for Primary Care Research, The University of Manchester, Manchester, UK e.kontopantelis@manchester.ac.uk.ORCID 0000-0001-6450-5815
Manchester Academic Health Science Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAge and socioeconomic status (SES) predict several health-related outcomes, including prescription opioid use. Contrasting findings from previous literature found higher prevalence of opioid use in both people over 65 years old and the working-age population of 35-55 years old. This study aimed to analyse if the association between age and opioid use is non-linear and differs in adults with different SES levels.

methodsThis cohort study used the Health Survey for England waves 1997-2014 data to investigate the shape of the correlation between reported opioid use and income decile, employment status and educational level. A semiparametric Generalised Additive Model was employed, so that linearity of correlation was not assumed. The shape of the relationship was assessed using the effective degrees of freedom (EDF).

resultsPositive correlation between age and reported opioid use, more linear in people in the highest income decile (EDF: 1.01, p<0.001) and higher education (EDF: 2.03, p<0.001) was observed. In people on lower income and with lower levels of education, the highes probability of reported opioid use was at around 40-60 years old and slowly decreased after that. Higher income decile and higher levels of education were predictors of a lower probability of reported opioid use (OR: 0.27, 95% CI: 0.21 to 0.36 and OR: 0.48, 95% CI: 0.41 to 0.57, respectively). There was no statistically significant difference in opioid use between employed and unemployed people.

conclusionThe relationship between age and the probability of prescribed opioid use varies greatly across different income and educations strata, highlighting different drivers in opioid prescribing across population groups. More research is needed into exploring patterns in opioid use in older people, particularly from disadvantaged socioeconomic backgrounds.

Indexed as

Analgesics, OpioidOpioid-Related DisordersAdultAgedCohort StudiesEnglandHealth SurveysHumansMiddle AgedPractice Patterns, Physicians'Social ClassAnalgesics, Opioidepidemiologypain managementsocial medicine

Identifiers

PMID36858476
PMCPMC9980331
OpenAlexW4322758236

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.