Evidence map›Paper›PMID 36858470›Full record

ArticleBMJ open2023

All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study.

Olivia Farrant, Mamadu Baldeh, Joseph Baio Kamara, Emma Bailey, Stephen Sevalie, Gibrilla Deen, James Baligeh Walter Russell, Daniel Youkee, Andy Jm Leather, Justine Davies and 1 more

Abstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olivia FarrantCentre for Global Health Partnerships, King's College London, London, UK olivia.farrant@doctors.org.uk.ORCID 0000-0002-2573-8808
Mamadu BaldehDepartment of Medicine, College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.ORCID 0000-0001-7772-1111
Joseph Baio KamaraDepartment of Medicine, College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Emma BaileyCentre for Global Health Partnerships, King's College London, London, UK.ORCID 0000-0002-1642-4110
Stephen Sevalie34 Military Hospital, Wilberforce, Freetown, Sierra Leone.
Gibrilla DeenDepartment of Medicine, College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
James Baligeh Walter RussellDepartment of Medicine, College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.ORCID 0000-0003-4732-6588
Daniel YoukeeCentre for Global Health Partnerships, King's College London, London, UK.ORCID 0000-0002-2383-4425
Andy Jm LeatherCentre for Global Health Partnerships, King's College London, London, UK.
Justine DaviesCentre for Global Health Partnerships, King's College London, London, UK.
Sulaiman LakohDepartment of Medicine, College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.

Funding

Medical Research Council MR/W000903/1
6 · The paper itself

Abstract

objectivesTo study the mortality of patients with COVID-19 in Sierra Leone, to explore the factors associated with mortality during the COVID-19 pandemic and to highlight the complexities of treating patients with a novel epidemic disease in a fragile health system. STUDY

designA prospective single-centre cohort study. Data were extracted from paper medical records and transferred onto an electronic database. Specific indicators were compared between survivors and non-survivors, using descriptive statistics in Stata V.17. STUDY

settingThe infectious diseases unit (IDU) at Connaught Hospital in Freetown, Sierra Leone

participantsParticipants were all patients admitted to the IDU between March and July 2020. AIMS OF STUDY: The primary outcome of the study was to examine the all-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone and the secondary outcome measures were to examine factors associated with mortality in patients positive for COVID-19.

results261 participants were included in the study. Overall, 41.3% of those admitted to the IDU died, compared with prepandemic in-hospital mortality of 23.8%. Factors contributing to the higher mortality were COVID-19 infection (aOR 5.61, 95% CI 1.19 to 26.30, p=0.02) and hypertension (aOR 9.30, 95% CI 1.18 to 73.27, p=0.03)

conclusionsThis study explores the multiple factors underpinning a doubling in facility mortality rate during the COVID-19 pandemic in Sierra Leone . It provides an insight into the realities of providing front-line healthcare during a pandemic in a fragile health system.

Indexed as

COVID-19Cohort StudiesHumansPandemicsProspective StudiesSierra LeoneCOVID-19EpidemiologyPublic health

Identifiers

PMID36858470
PMCPMC9979583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.