Evidence map›Paper›PMID 36857665›Full record

ArticleLab on a chip2023

Passive redirection filters minimize red blood cell contamination during neutrophil chemotaxis assays using whole blood.

Felix Ellett, Daniel Irimia

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Felix EllettBioMEMS Resource Center, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Shriners Hospital for Children, Harvard Medical School, Boston, Massachusetts, USA. fellett@mgh.harvard.edu.ORCID 0000-0003-4941-4346
Daniel IrimiaBioMEMS Resource Center, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Shriners Hospital for Children, Harvard Medical School, Boston, Massachusetts, USA. fellett@mgh.harvard.edu.ORCID 0000-0001-7347-2082
Shriners Hospitals for Children - Erie · US

Funding

Neutrophil Decision Making in Confined Environments in Health and DiseaseR01GM092804 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI IRIMIA, DANIEL · 2010 to 2022
$4.3M
Microfluidic Assays for Probing Neutrophil-Borrelia Interactions in Blood during Acute Lyme DiseaseR21AI156723 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI IRIMIA, DANIEL · 2021 to 2022
$462k
NIAID NIH HHS R21 AI156723NIGMS NIH HHS R01 GM092804
6 · The paper itself

Abstract

Neutrophils are the most numerous white blood cells and are the first to arrive at sites of inflammation and infection. Thus, neutrophil behavior provides a comprehensive biomarker for antimicrobial defenses. Several microfluidic tools have been developed to test neutrophil chemotaxis, phagocytosis, extrusion of extracellular traps,

Indexed as

ChemotaxisNeutrophilsChemotaxis, LeukocyteErythrocytesMicrofluidics

Identifiers

PMID36857665
PMCPMC11343506
OpenAlexW4321614197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.