Evidence map›Paper›PMID 36857576›Full record

ArticleBioinformatics (Oxford, England)2023

RSCanner: rapid assessment and visualization of RNA structure content.

Gandhar Mahadeshwar, Rafael de Cesaris Araujo Tavares, Han Wan, Zion R Perry, Anna Marie Pyle

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Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gandhar MahadeshwarDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, United States.
Rafael de Cesaris Araujo TavaresDepartment of Chemistry, Yale University, New Haven, CT 06511, United States.ORCID 0000-0003-0278-1528
Han WanDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, United States.
Zion R PerryDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, United States.ORCID 0000-0002-8375-8436
Anna Marie PyleDepartment of Chemistry, Yale University, New Haven, CT 06511, United States.

Funding

High-throughput detection of transcriptomic and epitranscriptomic variation and kinetics using MarathonRTR01HG011868 · NHGRI · YALE UNIVERSITY · PI GRAVELEY, BRENTON R., PYLE, ANNA MARIE · 2021 to 2024
$3.9M
NHGRI NIH HHS R01 HG011868
6 · The paper itself

Abstract

motivationThe increasing availability of RNA structural information that spans many kilobases of transcript sequence imposes a need for tools that can rapidly screen, identify, and prioritize structural modules of interest.

resultsWe describe RNA Structural Content Scanner (RSCanner), an automated tool that scans RNA transcripts for regions that contain high levels of secondary structure and then classifies each region for its relative propensity to adopt stable or dynamic structures. RSCanner then generates an intuitive heatmap enabling users to rapidly pinpoint regions likely to contain a high or low density of discrete RNA structures, thereby informing downstream functional or structural investigation. AVAILABILITY AND IMPLEMENTATION: RSCanner is freely available as both R script and R Markdown files, along with full documentation and test data (https://github.com/pylelab/RSCanner).

Indexed as

RNASoftwareDocumentationProtein Structure, SecondarySequence Analysis, RNARNA

Identifiers

PMID36857576
PMCPMC10017096

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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measurements read5
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.