ArticleAesthetic surgery journal2023
Microtoxin for Improving Pore Size, Skin Laxity, Sebum Control, and Scars: A Roundtable on Integrating Intradermal Botulinum Toxin Type A Microdoses Into Clinical Practice.
Article in Aesthetic surgery journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Efficacy and Safety of Microneedling Combined With Botulinum Toxin-A Versus Meso-Botox Injection in the Treatment of Atrophic Acne Scars: A Split-face Comparative Study
Effects of PrabotulinumtoxinA-xvfs on Facial Skin Quality, Fine Wrinkles, and Texture
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- How to Treat Skin Quality: A Consensus-Based Treatment Algorithm and Expert Guidance.Journal of cosmetic dermatology · 2025Guideline
- Comparison of Intradermal Injection with Mesotherapy of Botulinum Toxin Type A for Axillary Sweat Reduction: A Preliminary, Prospective, Randomized, Self-controlled Study.Aesthetic plastic surgery · 2026Trial
- Air-Botulinum Neurotoxin and Polydeoxyribonucleotide Injections for Acne Scar Treatment.Aesthetic plastic surgery · 2025Trial
- Comparison of Intradermal Versus Microneedling-Assisted Botulinum A Toxin Injection for Enlarged Facial Pores: A Randomized Clinical Trial.Journal of cosmetic dermatology · 2025Trial
- A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores.Toxins · 2025Trial
- Effects of Botulinum Toxin Type A and Argireline on Dermal Collagen Remodeling and Skin Biology in a Flap Model.Aesthetic plastic surgery · 2026Article
- Full-face aesthetic treatment with onabotulinumtoxin A: Results from a retrospective real world analysis.JPRAS open · 2026Article
- Transdermal Delivery of Botulinum Toxin for the Management of Oily and Acne-Prone Skin Using TDA Technology.Journal of cosmetic dermatology · 2026Observational
- Integrative Aesthetics: Shaping the Emerging Frontier of Modern Aesthetic Medicine.Clinical, cosmetic and investigational dermatology · 2026Review
- Review
- Microneedle for Botulinum Toxin: A Randomized, Case-control, Single-blind Study to Assess Clinical Efficacy and Patient Satisfaction.Plastic and reconstructive surgery. Global open · 2025Article
- Diamond Technique: A Triple Treatment for Neck and Décolletage Rejuvenation.Journal of cosmetic dermatology · 2025Article
- Efficacy of diluted botulinum toxin type A (Microbotox) in treatment of mild to moderate acne vulgaris.Archives of dermatological research · 2025Article
- Botulinum toxin on a mission to erase keloids: does the dream come true?Postepy dermatologii i alergologii · 2025Review
- Injectable "Skin Boosters" in Aging Skin Rejuvenation: A Current Overview.Archives of plastic surgery · 2024Article
- Intradermal Botulinum Toxin A on Skin Quality and Facial Rejuvenation: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2024Article
- Atrophic Postacne Scar Treatment: Narrative Review.JMIR dermatology · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundIn aesthetic clinical practice, botulinum toxin type A (BoNT-A) is best known for its use as a neuromodulator for the treatment of dynamic facial lines; however, when injected intradermally as microdroplets, BoNT-A can improve skin quality and overall skin appearance.
objectivesTo discuss key aspects of microtoxin use in clinical practice and provide expert guidance on utilization.
methodsAs part of a continuing medical education lecture series and roundtable, the authors discussed key aspects of microtoxin patient selection, injection technique, and safety.
resultsThe experiences of expert faculty are shared here. Clinical experience is consistent with reported data. Microtoxin can be used to reduce pore size, sebum production, rosacea, acne, and fine lines, and to improve jawline and neck definition. Intradermal injection can also be employed for the improvement of transverse neck lines as well as for the safe prevention and management of scars and keloids.
conclusionsExpanding the use of BoNT-A, a predictable, minimally invasive, and affordable treatment to address commonly encountered complaints is appealing. The authors have found that making patients aware of microtoxin as a treatment option results in an increased interest in and utilization of BoNT-A, and high satisfaction among appropriately selected patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.