Evidence map›Paper›PMID 36857454›Full record

ArticleScience advances2023

Functional imaging and quantification of multineuronal olfactory responses in

Albert Lin, Shanshan Qin, Helena Casademunt, Min Wu, Wesley Hung, Gregory Cain, Nicolas Z Tan, Raymond Valenzuela, Leila Lesanpezeshki, Vivek Venkatachalam and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  15. A simple yet reliable assay for chemotaxis inmicroPublication biology · 2025
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  16. Valeric acid attractsmicroPublication biology · 2025
    Article
  17. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Albert LinDepartment of Physics, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-4541-5889
Shanshan QinCenter for Brain Science, Harvard University, Cambridge, MA, USA.ORCID 0000-0001-8012-5687
Helena CasademuntDepartment of Physics, Harvard University, Cambridge, MA, USA.ORCID 0000-0003-4644-2536
Min WuLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.ORCID 0000-0003-2674-6452
Wesley HungLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.ORCID 0000-0001-8488-7638
Gregory CainDepartment of Physics, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-2880-2692
Nicolas Z TanDepartment of Physics, Northeastern University, Boston, MA, USA.
Raymond ValenzuelaDepartment of Physics, Northeastern University, Boston, MA, USA.
Leila LesanpezeshkiLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.ORCID 0000-0001-8111-4314
Vivek VenkatachalamDepartment of Physics, Northeastern University, Boston, MA, USA.ORCID 0000-0002-2414-7416
Cengiz PehlevanCenter for Brain Science, Harvard University, Cambridge, MA, USA.ORCID 0000-0001-9767-6063
Mei ZhenLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.ORCID 0000-0003-0086-9622
Aravinthan D T SamuelDepartment of Physics, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-1672-8720
Harvard University · USMount Sinai Hospital · CANortheastern University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Comprehensive Analysis of a Decision CircuitUF1NS111697 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PEHLEVAN, CENGIZ, SAMUEL, ARAVINTHAN D. · 2019 to 2019
$3.0M
Development and Divergence of Whole-Brain ActivityR01NS126334 · NINDS · NORTHEASTERN UNIVERSITY · PI Vivek Venkatachalam · 2022 to 2026
$2.1M
NIH HHS P40 OD010440NINDS NIH HHS R01 NS126334NINDS NIH HHS UF1 NS111697
6 · The paper itself

Abstract

Many animals perceive odorant molecules by collecting information from ensembles of olfactory neurons, where each neuron uses receptors that are tuned to recognize certain odorant molecules with different binding affinity. Olfactory systems are able, in principle, to detect and discriminate diverse odorants using combinatorial coding strategies. We have combined microfluidics and multineuronal imaging to study the ensemble-level olfactory representations at the sensory periphery of the nematode

Indexed as

Caenorhabditis elegansSmellAnimalsMicrofluidicsOdorantsSensory Receptor Cells

Identifiers

PMID36857454
PMCPMC9977185
OpenAlexW4322726757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.