Evidence map›Paper›PMID 36857016›Full record

ArticleJournal of neurovirology2023

HIV viremia contributes to neurocognitive impairments in persons who use cocaine.

Kareem Al-Khalil, Sheri L Towe, Taylor P Ikner, Christina S Meade

Open access · greenAbstract read
In one paragraph

Article in Journal of neurovirology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kareem Al-KhalilDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Duke University, Durham, NC, USA. kareem.alkhalil@duke.edu.ORCID 0000-0003-1387-6733
Sheri L ToweDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Duke University, Durham, NC, USA.
Taylor P IknerCollege of Liberal and Professional Studies, University of Pennsylvania, Philadelphia, PA, USA.
Christina S MeadeDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Duke University, Durham, NC, USA.
Duke University · USUniversity of Pennsylvania · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Decision Making and HIV Risk: New Approaches to neuroAIDS Research in Drug UsersDP2DA040226 · NIDA · DUKE UNIVERSITY · PI MEADE, CHRISTINA S · 2015 to 2015
$2.4M
MRI data fusion to investigate effects of drug abuse on HIV neurological complicationsR01DA045565 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MEADE, CHRISTINA S · 2018 to 2022
$2.0M
NIAID NIH HHS P30 AI064518NIDA NIH HHS DP2 DA040226NIDA NIH HHS R01 DA045565
6 · The paper itself

Abstract

Persons with HIV (PWH) who use illicit drugs are at elevated risk for neurocognitive impairment (NCI). This study investigated the effects of HIV disease and HIV viremia on NCI among adults who use cocaine. PWH who were not virologically suppressed showed greater global deficits compared to participants with HIV viral suppression and HIV-negative participants, but no differences emerged between the latter two groups. These findings highlight the adverse effects of poorly controlled HIV disease on NCI, beyond the independent effects of cocaine on cognition, and underscore the importance of strengthening the HIV care continuum for persons who use cocaine.

Indexed as

CocaineHIV InfectionsAdultCognitionHumansNeuropsychological TestsViremiaCocaineCocaine useHIVNeuropsychological impairmentViral loadViral suppression

Identifiers

PMID36857016
PMCPMC11060036
OpenAlexW4322720116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.