Evidence map›Paper›PMID 36856913›Full record

Trial reportTechniques in coloproctology2023

Local anaesthetic for pain post rubber band ligation of haemorrhoids: a prospective, single-blinded randomised controlled trial.

C Steen, Y M Cho, M Scott, A Jain, V Balakrishnan, J Keck, V An, R Chandra

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Techniques in coloproctology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

C SteenDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia. drcjsteen@gmail.com.ORCID http://orcid.org/0000-0001-5057-6436
Y M ChoDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia.
M ScottSwinburne University, VIC, Melbourne, Australia.
A JainDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia.
V BalakrishnanDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia.
J KeckDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia.
V AnDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia.
R ChandraDepartment of Colorectal Surgery, Eastern Health, 8 Arnold Street, Box Hill, Victoria, Australia.
Eastern Health · AUSwinburne University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRubber band ligation (RBL) is a widely accepted intervention for the treatment of haemorrhoids. However, post procedure pain is a common complaint. The aim of this study was to determine whether the addition of local anaesthetic (LA) to the haemorrhoid pedicle base, post RBL, aids in reducing early post-procedure pain. Additionally, to compare perceived perianal numbness, oral analgesia usage and total consumption, and adverse events.

methodsThis study was a prospective, single-blinded randomised controlled trial. Patients were recruited from colorectal clinics in two Australian hospitals between 2018-2019. Patients randomised to the intervention (LA) group received 2mls bupivacaine 0.5% with adrenaline 1:200,000 to each haemorrhoid base. Patients in the control group were not administered LA. Pain scores were recorded over 48 h using visual analogue scales. Analgesia consumption was documented and other secondary objectives were recorded dichotomously (yes/no).

resultsAt 1 h post-procedure, patient reported pain scores were significantly lower in the LA group compared to the control group (p = 0.04). There were no significant differences in pain scores between the groups at 4, 24 or 48 h. Additionally, there were no significant differences between groups with respect to oral analgesia usage, perianal numbness or adverse events.

conclusionsLA to the haemorrhoid pedicle post RBL may significantly reduce early post procedure pain without any increased risk of adverse effects.

Indexed as

HemorrhoidsProcedural PainAnesthetics, LocalAustraliaHumansHypesthesiaLigationPostoperative PainProspective StudiesAnesthetics, LocalAnalgesiaBupivacaineHaemorrhoidLocal anaestheticOpioidRubber band ligation

Identifiers

PMID36856913
OpenAlexW4322719382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.