Evidence map›Paper›PMID 36856821›Full record

ArticleAnalytical and bioanalytical chemistry2023

A simple and sensitive electrochemical sensor for the detection of peptidase activity.

Tiantian Dai, Mingyue Qiu, Hongyu Li, Mingyan Yang, Jie Gao, Xinmin Li, Jiajia Lv, Minghui Yang, Zeli Yuan, Junjun Luo

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tiantian DaiCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Mingyue QiuCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Hongyu LiCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Mingyan YangCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Jie GaoCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Xinmin LiCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Jiajia LvCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China.
Minghui YangKey Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China. yangminghui@csu.edu.cn.
Zeli YuanCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China. zlyuan@zmu.edu.cn.
Junjun LuoCollege of Pharmacy, Zunyi Medical University, Zunyi, 563003, Guizhou, China. luojunjun8868@163.com.
Theranostics (New Zealand) · NZZunyi Medical University · CNCentral South University · CN

Funding

Science and Technology Fund Project of Guizhou Provincial Health Commission gzwkj2022-207Zunyi Science and Technology Plan Project Zunshikehe HZ [2022] 383
6 · The paper itself

Abstract

In this work, a simple and sensitive electrochemical sensor was proposed for the detection of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) activity. Firstly, the BACE1 specific peptide was modified onto the Au electrode to graft a single-strand DNA with polycytosine DNA sequence (dC

Indexed as

Alzheimer DiseaseAmyloid Precursor Protein SecretasesAmyloid beta-PeptidesAspartic Acid EndopeptidasesBase SequenceHumansPeptidesAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesPeptidesAlzheimer’s diseaseBACE1Electrochemical sensorMolybdateRedox molybdophosphateβ-Site amyloid precursor protein cleaving enzyme 1

Identifiers

PMID36856821
OpenAlexW4322719465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.