Evidence map›Paper›PMID 36856418›Full record

ArticlemBio2023

A New Phenotype in

Arianna Sala, Andrea Ardizzoni, Luca Spaggiari, Nikhil Vaidya, Jane van der Schaaf, Cosmeri Rizzato, Claudio Cermelli, Selene Mogavero, Thomas Krüger, Maximilian Himmel and 10 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Phenotypic and genotypic analysis ofInfection and immunity · 2026
    Article
  4. Differential Virulence of VaginalJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Interactions betweenInfection and immunity · 2026
    Article
  10. Article
  11. Recent progress in understanding ferroptosis mechanisms in infectious diseases.Frontiers in cellular and infection microbiology · 2026
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Vaginal Clinical Isolates ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  17. Review
  18. Microorganisms · 2025
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 3 countries.

Arianna SalaDepartment of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0003-0766-7943
Andrea ArdizzoniDepartment of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Luca SpaggiariClinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0003-1369-0955
Nikhil VaidyaDepartment of Molecular and Biomedical Sciences, University of Maine, Orono, Maine, USA.
Jane van der SchaafDepartment of Molecular and Biomedical Sciences, University of Maine, Orono, Maine, USA.
Cosmeri RizzatoDepartment of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Claudio CermelliDepartment of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Selene MogaveroDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.
Thomas KrügerDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.
Maximilian HimmelDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.
Olaf KniemeyerDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.
Axel A BrakhageDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.ORCID 0000-0002-8814-4193
Benjamin L KingDepartment of Molecular and Biomedical Sciences, University of Maine, Orono, Maine, USA.
Antonella LupettiDepartment of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.ORCID 0000-0002-6975-8114
Manola ComarInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
Francesco de SetaInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
Arianna TavantiDepartment of Biology, University of Pisa, Pisa, Italy.
Elisabetta BlasiDepartment of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-4202-8293
Robert T WheelerDepartment of Molecular and Biomedical Sciences, University of Maine, Orono, Maine, USA.ORCID 0000-0003-3223-7021
Eva PericoliniDepartment of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-5299-8197
University of Modena and Reggio Emilia · ITLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEUniversity of Maine · USUniversity of Pisa · ITUniversity of Trieste · IT

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Intravital study of innate immunity to mucosal candidiasisR15AI133415 · NIAID · UNIVERSITY OF MAINE ORONO · PI WHEELER, ROBERT T. · 2018 to 2018
$415k
NIAID NIH HHS R15 AI133415NIGMS NIH HHS P20 GM103423NIH HHS P20GM103423NIH HHS R15AI133415
6 · The paper itself

Abstract

Vulvovaginal candidiasis (VVC) affects nearly 3/4 of women during their lifetime, and its symptoms seriously reduce quality of life. Although Candida albicans is a common commensal, it is unknown if VVC results from a switch from a commensal to pathogenic state, if only some strains can cause VVC, and/or if there is displacement of commensal strains with more pathogenic strains. We studied a set of VVC and colonizing C. albicans strains to identify consistent

Indexed as

Candidiasis, VulvovaginalAntifungal AgentsCandidaCandida albicansCell CommunicationFemaleHumansMultilocus Sequence TypingPhenotypeQuality of LifeAntifungal AgentsCandida albicansepithelial cellshost-pathogen interactionsinterferonsvulvovaginal candidiasis

Identifiers

PMID36856418
PMCPMC10128025
OpenAlexW4322718661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.