ArticleTurkish archives of pediatrics2023
Clinical and Laboratory Features and Factors Determining the Outcome in Poisoning Children in a Tertiary Pediatric Intensive Care Unit: Eleven Years of Experience.
Article in Turkish archives of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Etiology, Clinical Features, and Outcomes of Acute Poisoning Among Children at a Provincial Pediatric Hospital in Vietnam: Retrospective Descriptive Study.JMIR formative research · 2026Article
- Accuracy of Pediatric new poisoning mortality score versus poisoning severity score in prediction of in-hospital mortality of acutely poisoned children admitted to Pediatric intensive care unit.Toxicology research · 2025Article
- Global, regional, and national burden of unintentional childhood poisoning, 1990-2021: an analysis of data from the Global Burden of Disease study 2021.Frontiers in public health · 2025Article
- Patterns and Outcomes of Acute Poisoning Among Children Presenting to Emergency Department in AlAhsa, Saudi Arabia.Cureus · 2024Article
- Patterns and clinical outcomes of childhood poisoning presenting to a children's emergency department in Yenagoa, Nigeria: a 10-year retrospective study.BMJ paediatrics open · 2024Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to evaluate the characteristics of patients admitted to a pediatric intensive care unit for poisoning and the factors associated with their outcomes. MATERIALS AND
methodsPatients who were admitted to the pediatric intensive care unit for poisoning over the 11-year period between January 2010 and December 2020 were retrospectively analyzed. The patients' demographic characteristics, poisoning agent, whether the poisoning was unintentional or intentional (suicide attempt), clinical findings at admission, indication for hospitalization, antidote administered, and supportive and extracorporeal treatments were examined.
resultsDuring the study period, poisonings accounted for 9.4% (436/4653) of pediatric intensive care unit admissions. Of these, 419 patients with complete records were included in the analysis. Drug poisonings accounted for 81.9% of cases (multiple drugs in 38.5%). The most common drug group was central nervous system drugs (47%). Of the symptomatic patients, 56.5% had central nervous system-related findings and 55% had gastrointestinal findings. Before pediatric intensive care unit admission, 52.7% of the patients received activated charcoal and 7.4% received antidote therapy. In the pediatric intensive care unit, 68.9% of patients received no medical treatment, while 71.5% of those who received medical treatment had organ involvement. Multivariate logistic regression analysis to predict whether patients will require treatment during the intensive care follow-up showed that antidote administration before pediatric intensive care unit admission was associated with the need for medical treatment (odds ratio: 25.6, 95% CI: 6.8-96, P < .05). Three patients died, and the mortality rate was 0.72%.
conclusionChildhood poisoning is a widespread and important problem. Effective management in pediatric emergency and intensive care units contributes to patient survival without sequelae.
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Registered trials
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