ArticleTurkish archives of pediatrics2023
The Spectrum of Childhood Tuberculosis in an African Setting: A Hospital-Based Experience in Bamenda, Cameroon.
Article in Turkish archives of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Prevalence and determinants of unsuccessful tuberculosis treatment outcomes among children in Northern Ghana: a retrospective review.BMC infectious diseases · 2026Article
- High treatment success among individuals with rifampicin-resistant tuberculosis in Botswana: A retrospective cohort study.Journal of infection and public health · 2026Article
- GeneXpert MTB/RIF Ultra in Pediatric Tuberculosis: How Disease Characteristics Modify Test Performances.Current pediatric reviews · 2026Article
- Immune Sensitization toPathogens (Basel, Switzerland) · 2025Article
- Atypical Mycobacterial Pneumonia in 2 Siblings with a Novel Hypomorphic NEMO/IKBKG Mutation.Turkish archives of pediatrics · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
objectiveDifficulty in confirming childhood tuberculosis leads to late diagnosis and subsequently poor outcomes. This study aimsto determinethe epidemiology, clinical features, diagnostic modalities, and outcomes of childhood tuberculosis at the Bamenda Regional Hospital. MATERIALS AND
methodsThis was a retrospective study involving childrenaged between0-15 years with confirmed tuberculosis fromJanuary 1, 2012, to December 31, 2021. We excluded children without proven tuberculosis diagnosis. Data were obtained from files using predesigned data collection forms.
resultsIn total, 108 proven cases of childhood tuberculosis were managed in our study period out of which 86 fulfilled our inclusion criteria and were recruited. This gave a prevalence of 4.5% at the Bamenda Regional Hospital. The mean age of the children was 9.6±4.5years. We had a sex ratio of 0.8. The most frequent presenting symptoms were cough (98.8%) and fever (87.2%). Gene Xpert confirmed the diagnosis in 96.2% of the children, smear microscopy in 88.5%, and histopathological analysis in 100% of biopsied specimens. Non-cavitating lesions (43.6%) were the most frequent chest x-ray finding. The majority of the childhood tuberculosis cases were pulmonary (96.5%). Most children (76.7%) were cured and the mortality was 11.3%. The risk of death of children younger than 5 years (P= .015)wasincreased 9 times.
conclusionsWe found the prevalence of childhood tuberculosis to be 4.5% at the Bamenda Regional Hospital. Most children presented with cough, fever, and weight loss. There was a high cure rate and low mortality, and age less than 5 years significantly increased the risk of mortality.
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