Evidence map›Paper›PMID 36856269›Full record

ArticleeLife2023

Controlling periodic long-range signalling to drive a morphogenetic transition.

Hugh Z Ford, Angelika Manhart, Jonathan R Chubb

Open access · goldFull text read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Many Cells Make Light Work: Self-Generated Gradients OrganizeCold Spring Harbor perspectives in biology · 2026
    Review
  2. Article
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  8. Nematic cell alignment directs calcium waves.bioRxiv : the preprint server for biology · 2025
    Article
  9. Pattern formation along signaling gradients driven by active droplet behavior of cell swarms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hugh Z FordLaboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, London, United Kingdom.ORCID 0000-0002-0457-7224
Angelika ManhartDepartment of Mathematics, University College London, London, United Kingdom.
Jonathan R ChubbLaboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, London, United Kingdom.ORCID 0000-0001-6898-9765
MRC Laboratory for Molecular Cell Biology · GBUniversity of Vienna · AT

Funding

Wellcome TrustWellcome Trust 202867/Z/16/Z
6 · The paper itself

Abstract

Cells use signal relay to transmit information across tissue scales. However, the production of information carried by signal relay remains poorly characterised. To determine how the coding features of signal relay are generated, we used the classic system for long-range signalling: the periodic cAMP waves that drive

Indexed as

DictyosteliumCyclic AMPModels, BiologicalMorphogenesisSignal TransductionCyclic AMPcollective migrationdevelopmental biologydictyosteliumexcitable mediafrequency codingmorphogenesisphysics of living systemssignal relayspiral wave

Identifiers

PMID36856269
PMCPMC10027319
OpenAlexW4322719995

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
table measurements read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.