Evidence map›Paper›PMID 36856204›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[A multi-center analysis of thyroid-stimulating hormone level in apparently healthy elderly population in China].

K Wang, H Li, X Deng, S Yan, Y Qiu, Y Cong

Abstract readMulticenter StudyEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

K WangDepartment of Clinical Laboratory, National Clinical Research Center for Geriatric Diseases, Second Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
H LiDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
X DengDepartment of Clinical Laboratory, National Clinical Research Center for Geriatric Diseases, Second Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
S YanDepartment of Endocrinology, National Clinical Research Center for Geriatric Diseases, Second Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Y QiuDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Y CongDepartment of Clinical Laboratory, National Clinical Research Center for Geriatric Diseases, Second Medical Center of Chinese PLA General Hospital, Beijing 100853, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate serum thyroid stimulating hormone (TSH) level and its changes with age in apparently healthy Chinese elderly population and analyze the differences between TSH levels detected using Roche and Snibe electrochemiluminescence immunoassay analyzers.

methodsGeneral clinical data and frozen fasting serum samples were collected from 5451 apparently healthy Chinese elderly individuals (> 60 years) from 10 centers in different geographic regions in China. Thyroid function indexes including TSH level were detected using Roche and Snibe electrochemiluminescence immunoassay analyzer, and the median (2.5% and 97.5% quantiles) TSH level was calculated. The variations of TSH level among the participants with geographic regions, gender, and age (with an interval of 5 years) were analyzed to determine the influence of these factors on TSH level.

resultsThe reference ranges of serum TSH level established using Roche and Snibe electrochemiluminescence immunoassay analyzers were 0.42-9.47 mU/L and 0.36-7.98 mU/L, respectively, showing significant differences between the two methods (

conclusionIn elderly population, serum TSH level can vary with geographic region, gender, and age, but there was no need for establishing specific reference ranges for these factors. The differences between different detection methods should be evaluated when interpreting the detection results of TSH level.

Indexed as

Asian PeopleThyrotropinAgedChinaFastingFemaleHealth StatusHumansMaleMiddle AgedThyrotropinelderly populationgenderreference rangethyroid-stimulating hormone

Identifiers

PMID36856204
PMCPMC9978719

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