ArticleBiology letters2023
Early conversion of maternal androgens affects the embryo already in the first week of development.
Article in Biology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Transcriptome analysis of early embryonic development in a mouse model of polycystic ovary syndrome.Frontiers in cell and developmental biology · 2025Article
- Effects of maternal androgens and their metabolite etiocholanolone on prenatal development in birds.The Journal of experimental biology · 2024Article
- In ovo injection of testosterone to yolk sac modulates early posthatching development and physiology of male chick in broilers.Poultry science · 2024Article
- Early conversion of maternal androgens affects the embryo already in the first week of development.Biology letters · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal androgen exposure has potent effects on offspring development. As substantial levels of maternal androgens are deposited in avian egg yolks, avian eggs are frequently used to study maternal effects, with a strong focus on post-natal development. However, the underlying pathways are largely unknown. Since the hormones are taken up during the embryonic phase, and these are rapidly metabolized by avian embryos into metabolites such as etiocholanolone, we studied the effects of yolk androgens (testosterone and androstenedione) and their metabolite etiocholanolone during the first few days of embryonic development. As embryonic heart rate is often used as an indicator of embryonic development, we measured the heart rate from day 3 to day 6 of incubation by using a shell-less culture technique in rock pigeon eggs (
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Registered trials
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