Evidence map›Paper›PMID 36855648›Full record

ReviewHeliyon2023

An update on COVID-19: SARS-CoV-2 variants, antiviral drugs, and vaccines.

Varghese Edwin Hillary, Stanislaus Antony Ceasar

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 3 pooled it
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Journal of microbiology and biotechnology · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Identification of potential SARS-CoV-2 MJournal of computer-aided molecular design · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Extracellular vesicles in viral disease management.Current research in microbial sciences · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Myocarditis incidence and hospital mortality from 2007 to 2022: insights from a nationwide registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  15. Integrating Chemo- and Bioinformatics withJournal of chemical information and modeling · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution.

Varghese Edwin HillaryDepartment of Biosciences, Rajagiri College of Social Sciences, Cochin, 683 104, Kerala, India.
Stanislaus Antony CeasarDepartment of Biosciences, Rajagiri College of Social Sciences, Cochin, 683 104, Kerala, India.
Rajagiri College of Social Sciences (Autonomous)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious and pathogenic virus that first appeared in late December 2019. This SARS-CoV-2 causes an infection of an acute respiratory disease called "coronavirus infectious disease-2019 (COVID-19). The World Health Organization (WHO) declared this SARS-CoV-2 outbreak a great pandemic on March 11, 2020. As of January 31, 2023, SARS-CoV-2 recorded more than 67 million cases and over 6 million deaths. Recently, novel mutated variants of SARS-CoV are also creating a serious health concern worldwide, and the future novel variant is still mysterious. As infection cases of SARS-CoV-2 are increasing daily, scientists are trying to combat the disease using numerous antiviral drugs and vaccines against SARS-CoV-2. To our knowledge, this is the first comprehensive review that summarized the dynamic nature of SARS-CoV-2 transmission, SARS-CoV-2 variants (a variant of concern and variant of interest), antiviral drugs and vaccines utilized against SARS-CoV-2 at a glance. Hopefully, this review will enable the researcher to gain knowledge on SARS-CoV-2 variants and vaccines, which will also pave the way to identify efficient novel vaccines against forthcoming SARS-CoV-2 strains.

Indexed as

ACE2, Angiotensin-converting enzyme 2Antiviral drugsCOVID-19COVID-19, Coronavirus infectious disease-2019EUA, Emergency Use AuthorizationFDA, Food and Drug AdministrationNIH, National Institutes of HealthRBD, Receptor-binding domainSARS-CoV-2SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2SARS-CoV-2 variantsVaccinesVOC, Variants of ConcernVOI, Variants of InterestsWHO, World Health Organization

Identifiers

PMID36855648
PMCPMC9946785
OpenAlexW4321602120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.