Evidence map›Paper›PMID 36855137›Full record

ArticleEuropean journal of medical research2023

Change of serum lipoproteins and its potential use in stratifying patients with sepsis among neonates.

Junfei Guo, Weiming Lai, Yongbing Wu, Huan Li, Zhenhua Fu, Xiaoping Mu

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Junfei GuoClinical Laboratory Department, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Weiming LaiClinical Laboratory Department, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Yongbing WuClinical Laboratory Department, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Huan LiClinical Laboratory Department, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Zhenhua FuClinical Laboratory Department, Guangdong Women and Children Hospital, Guangzhou, 511400, China. fisher328@sina.com.
Xiaoping MuClinical Laboratory Department, Guangdong Women and Children Hospital, Guangzhou, 511400, China. muxiaoping710@126.com.
Guangdong Province Women and Children Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanges of serum lipoprotein concentration during bacteremia or sepsis are observed and lipoproteins concentration facilitate the evaluation severity of sepsis in adults, but its clinical usage is still unclear. Here, we analyzed the lipoprotein concentration in neonates with sepsis and discussed its use in stratifying patients.

methodsThis is a retrospective study involved 88 culture-proven septic patients. Clinical and microbiology data of involved patients were collected via inquiring databases of our institute. Patients were grouped according to blood culture results or procalcitonin level; the difference between groups were analyzed.

resultsCompared with uninfected group, there is no change of triglyceride (TG) concentrations and significant decrease of Total cholesterol (TC) concentration in septic patients. There is no significant difference between Gram-positive and Gram-negative-related septic patients in terms of serum TG and TC concentration. Other than group with procalcitonin level of 0.5-2 ng/ml, both serum TG and TC concentration were decreased while serum procalcitonin level increasing.

conclusionsOur results indicated that serum lipoprotein concentration may be recommended to help diagnosis of bacteria and to evaluate the severity of sepsis.

Indexed as

BacteremiaLipoproteinsSepsisHumansInfant, NewbornProcalcitoninRetrospective StudiesLipoproteinsProcalcitoninBacteremiaHDL-CLDL-CLipoproteinsSepsis

Identifiers

PMID36855137
PMCPMC9976484
OpenAlexW4322719871

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.