ArticleGenome biology2023
correctKin: an optimized method to infer relatedness up to the 4th degree from low-coverage ancient human genomes.
Article in Genome biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- IBS-CNN: a novel computer vision-based kinship classification model for high-density SNP microarray.International journal of legal medicine · 2026Article
- Genetic identification of Árpád Dynasty members from the ossuary of the Royal Basilica at Székesfehérvár.iScience · 2026Article
- Fault-tolerant pedigree reconstruction from pairwise kinship relations.Bioinformatics (Oxford, England) · 2026Article
- Evaluating the performance of ancient DNA genetic relatedness estimation methods using high-fidelity pedigree simulations.Genome biology · 2026Article
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- Genomic analyses support locally derived crown-of-thorns seastar outbreaks in the Pacific.BMC biology · 2025Article
- Optimizing sequence data analysis using convolution neural network for the prediction of CNV bait positions.BMC bioinformatics · 2024Article
- A brief guide to analyzing expression quantitative trait loci.Molecules and cells · 2024Review
- Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary.iScience · 2024Article
- READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics.Genome biology · 2024Article
- Genomic ancestry and social dynamics of the last hunter-gatherers of Atlantic France.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- correctKin: an optimized method to infer relatedness up to the 4th degree from low-coverage ancient human genomes.Genome biology · 2023Article
- KIN: a method to infer relatedness from low-coverage ancient DNA.Genome biology · 2023Article
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7 authors.
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Abstract
Kinship analysis from very low-coverage ancient sequences has been possible up to the second degree with large uncertainties. We propose a new, accurate, and fast method, correctKin, to estimate the kinship coefficient and the confidence interval using low-coverage ancient data. We perform simulations and also validate correctKin on experimental modern and ancient data with widely different genome coverages (0.12×-11.9×) using samples with known family relations and known/unknown population structure. Based on our results, correctKin allows for the reliable identification of relatedness up to the 4th degree from variable/low-coverage ancient or badly degraded forensic whole genome sequencing data.
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