Evidence map›Paper›PMID 36855023›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023

The association of MIND diet with cognitive resilience to neuropathologies.

Maude Wagner, Puja Agarwal, Sue E Leurgans, David A Bennett, Julie A Schneider, Ana W Capuano, Francine Grodstein

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  5. MIND diet-related plasma proteins are associated with Alzheimer's disease risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maude WagnerRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0002-1834-3218
Puja AgarwalRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Sue E LeurgansRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Julie A SchneiderRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Ana W CapuanoRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Francine GrodsteinRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Characterizing the Behavior Profile of Healthy Cognitive AgingR01AG034374 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI PATRICIA A BOYLE · 2009 to 2026
$8.8M
Diet Patterns and Alzheimer Disease and Other DementiasR01AG054476 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI SCHNEIDER, JULIE A. · 2017 to 2021
$2.3M
EXERCISE, DISABILITY, OSTEOARTHRITIS AND COSTSR01AG015815 · NIA · STANFORD UNIVERSITY · PI FRIES, JAMES F · 2000 to 2006
$1.9M
NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG015815NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG034374NIA NIH HHS R01 AG054476
6 · The paper itself

Abstract

introductionCognitive resilience (CR) can be defined as the continuum of better through worse than expected cognition, given the degree of neuropathology. The relation of healthy diet patterns to CR remains to be elucidated.

methodsUsing longitudinal cognitive data and post mortem neuropathology from 578 deceased older adults, we examined associations between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet at baseline and two standardized CR measures reflecting higher cognitive levels over time (CR

resultsCompared to individuals in the lowest tertile of MIND score, those in the top tertile had higher CR DISCUSSION: The MIND diet is associated with both higher cognition and slower rates of cognitive decline, after controlling for neuropathology, indicating the MIND diet may be important to cognitive resilience.

Indexed as

Cognition DisordersCognitive DysfunctionDietary Approaches To Stop HypertensionDiet, MediterraneanAgedCognitionHumansAlzheimer's dementiacognitive resiliencelongitudinal studyMediterranean-DASH Intervention for Neurodegenerative Delay dietneuropathologynutrition

Identifiers

PMID36855023
PMCPMC10460833

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.