Evidence map›Paper›PMID 36854994›Full record

ArticleUpdates in surgery2023

Laparoscopy-assisted vs open total gastrectomy with D2 lymphadenectomy for advanced gastric cancer: results of a retrospective, multicenter study.

Giulio Illuminati, Antonio D'Urso, Enrico Fiori, Saverio Cerasari, Priscilla Nardi, Alfonso Lapergola, Rocco Pasqua, Salvatore Sorrenti, Daniele Pironi, Augusto Lauro and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Updates in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Giulio IlluminatiDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy. giulio.illuminati@uniroma1.it.ORCID http://orcid.org/0000-0001-8773-8523
Antonio D'UrsoService de Chirurgie Digestive et Viscérale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Enrico Fiori"Pietro Valdoni" Department of Surgery, University of Rome "La Sapienza", Rome, Italy.
Saverio CerasariDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Priscilla NardiDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Alfonso LapergolaService de Chirurgie Digestive et Viscérale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Rocco PasquaDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Salvatore SorrentiDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Daniele PironiDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Augusto LauroDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Vito D'AndreaDepartment of Surgical Sciences, University of Rome "La Sapienza", Rome, Italy.
Sapienza University of Rome · ITHôpitaux Universitaires de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to retrospectively compare the results of laparoscopy-assisted total gastrectomy (LATG) with those of open total gastrectomy (OTG) for advanced gastric cancer. Patients undergoing total gastrectomy for a T4a, N0-3a-b, M0 gastric adenocarcinoma were divided into two groups. Patients in group A (n = 122) underwent LAG, whereas patients in group B (n = 109) underwent OTG. Mean length of follow-up was 39 months. Primary study's endpoints were postoperative mortality and morbidity, overall late survival (OS) and disease-free survival (DFS). Secondary endpoints were the number of retrieved lymph nodes, operating time, intraoperative blood loss, postoperative length of stay (LOS) and the incidence of local recurrence. Twenty-four patients in group A (19.6%) required conversion into OTG. Postoperative mortality was absent in both groups. Postoperative morbidity was 19% in group A and 11% in group B [p = 0.19]. OS was 34% in group A and 42% in group B [p = 0.21]. DFS was 29% in group A and 33% in group B [p = 0.49]. Mean number of retrieved lymph nodes was 29 in group A and 34 in group B [p < 0.01]. Mean intraoperative blood loss was 230 ml in group A and 180 ml in group B [p = 0.02]. Mean postoperative LOS was 9 days in group A and 11 days in group B [p = 0.09]. Local recurrence was 19% in group A and 13% in group B [p = 0.20]. For advanced gastric cancer, OTG favorably compares with LATG.

Indexed as

LaparoscopyStomach NeoplasmsGastrectomyHumansLymph Node ExcisionPostoperative ComplicationsRetrospective StudiesTreatment OutcomeGastric cancerLaparoscopy-assisted gastrectomyLymphadenectomyOpen surgery

Identifiers

PMID36854994
OpenAlexW4322625245

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.