Evidence map›Paper›PMID 36854772›Full record

ArticleExperimental & molecular medicine2023

Inhibition of mitochondrial phosphate carrier prevents high phosphate-induced superoxide generation and vascular calcification.

Nhung Thi Nguyen, Tuyet Thi Nguyen, Ha Thu Nguyen, Ji-Min Lee, Min-Ji Kim, Xu-Feng Qi, Seung-Kuy Cha, In-Kyu Lee, Kyu-Sang Park

Open access · goldAbstract read
In one paragraph

Article in Experimental & molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 19 citations in OpenAlex.

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  9. Elevated phosphate levels in CKD - a direct threat for the heart.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Nhung Thi NguyenDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Korea.
Tuyet Thi NguyenDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Korea. tuyet.nt@vinuni.edu.vn.
Ha Thu NguyenDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Korea.
Ji-Min LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.
Min-Ji KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.ORCID http://orcid.org/0000-0003-4303-502X
Xu-Feng QiKey Laboratory of Regenerative Medicine, Ministry of Education, Department of Developmental and Regenerative Biology, Jinan University, Guangzhou, China.
Seung-Kuy ChaDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID http://orcid.org/0000-0003-3201-7950
In-Kyu LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea. leei@knu.ac.kr.ORCID http://orcid.org/0000-0002-1655-0985
Kyu-Sang ParkDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Korea. qsang@yonsei.ac.kr.ORCID http://orcid.org/0000-0003-0322-9807
Yonsei University · KRKyungpook National University Hospital · KRHanoi Medical University · VNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular calcification is a serious complication of hyperphosphatemia that causes cardiovascular morbidity and mortality. Previous studies have reported that plasmalemmal phosphate (Pi) transporters, such as PiT-1/2, mediate depolarization, Ca

Indexed as

HyperphosphatemiaVascular CalcificationAnimalsCells, CulturedMersalylMiceMyocytes, Smooth MuscleOsteogenesisPhosphatesPhosphate Transport ProteinsRatsSuperoxidesMersalylPhosphatesPhosphate Transport ProteinsSuperoxides

Identifiers

PMID36854772
PMCPMC10073177
OpenAlexW4322621638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.