ArticleBiomechanics and modeling in mechanobiology2023
A parametric geometry model of the aortic valve for subject-specific blood flow simulations using a resistive approach.
Article in Biomechanics and modeling in mechanobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Evaluation of the Haemodynamic Behaviour of Stenosed Aortic Heart Valves Using Fluid Structure Interaction Modelling.International journal for numerical methods in biomedical engineering · 2026Article
- A Parametric Finite Element Analysis of Chick Embryo Aortic Valve Leaflet Biomechanics.Bioengineering (Basel, Switzerland) · 2026Article
- Coupling Models of Resistive Valves to Muscle Mechanics in Cardiac Fluid-Structure Interaction Simulations.International journal for numerical methods in biomedical engineering · 2025Article
- Design and evaluation of valve interventions using ex vivo biomechanical modeling: the Stanford experience.General thoracic and cardiovascular surgery · 2025Review
- Mechano-electrical-fluid interaction left-ventricle model for numerical evaluation of aortic valve hemodynamics.Frontiers in bioengineering and biotechnology · 2025Article
- Development of a standardized ovine aortic stenosis model: a pathomimetic platform for TAVI evaluation and durability testing.Frontiers in cardiovascular medicine · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
Cardiac valves simulation is one of the most complex tasks in cardiovascular modeling. Fluid-structure interaction is not only highly computationally demanding but also requires knowledge of the mechanical properties of the tissue. Therefore, an alternative is to include valves as resistive flow obstacles, prescribing the geometry (and its possible changes) in a simple way, but, at the same time, with a geometry complex enough to reproduce both healthy and pathological configurations. In this work, we present a generalized parametric model of the aortic valve to obtain patient-specific geometries that can be included into blood flow simulations using a resistive immersed implicit surface (RIIS) approach. Numerical tests are presented for geometry generation and flow simulations in aortic stenosis patients whose parameters are extracted from ECG-gated CT images.
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