Evidence map›Paper›PMID 36853446›Full record

ArticleArchives of microbiology2023

The phylogeny and divergence time of Ophiocordyceps sinensis and its host insects based on elongation factor 1 alpha.

Shan Li, Yunguo Zhu, Zixian Xu, Lingling Chen, Wenqian Wang, Zhou Cheng

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Article in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Shan Li *School of Life Science and Technology, Tongji University, 1239, Siping Road, Shanghai, 200092, People's Republic of China.
Yunguo Zhu *School of Life Science and Technology, Tongji University, 1239, Siping Road, Shanghai, 200092, People's Republic of China.
Zixian XuSchool of Life Science and Technology, Tongji University, 1239, Siping Road, Shanghai, 200092, People's Republic of China.
Lingling ChenSchool of Life Science and Technology, Tongji University, 1239, Siping Road, Shanghai, 200092, People's Republic of China.
Wenqian WangSchool of Life Science and Technology, Tongji University, 1239, Siping Road, Shanghai, 200092, People's Republic of China.
Zhou ChengSchool of Life Science and Technology, Tongji University, 1239, Siping Road, Shanghai, 200092, People's Republic of China. chengzhou@tongji.edu.cn.

Funding

National Natural Science Foundation of China 81673526
6 · The paper itself

Abstract

Ophiocordyceps sinensis Berk. is a fungal parasite that parasitizes the larvae of Hepialidae and is endemic to the Qinghai-Tibet Plateau (QTP). The phylogeny and divergence time of O. sinensis and its host insects were analyzed for 137 individuals from 48 O. sinensis populations based on the elongation factor 1 alpha (EF-1α) gene. Lower nucleotide variation, with only 7 and 16 EF-1α haplotypes, was detected in O. sinensis and its host insects, respectively. The isolated and broad distribution patterns coexisted in both O. sinensis and its host insects on the QTP. The divergence time estimates show that O. sinensis and its host insects originated later than 14.33 million years (Myr) and earlier than 23.60 Myr in the Miocene period, and the major differentiation occurred later than 4 Myr. Their origin and differentiation match well with the second and third uplifts of the QTP, respectively. The host insects from the O. sinensis populations distributed around Qinghai Lake are inferred as an ancient and relict species that has survived various geological events of the QTP. It is suitable to estimate the divergence times of both O. sinensis and its host insects from the same individuals using one gene: EF-1α. Our findings of the origin, phylogeny, and evolution of the endemic species also support the epoch of geological events on the QTP.

Indexed as

CordycepsInsectaPeptide Elongation Factor 1AnimalsLarvaPhylogenyPeptide Elongation Factor 1DifferentiationEF-1αHost insectsOphiocordyceps sinensisOriginPhylogenyQinghai–Tibet Plateau

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.