Evidence map›Paper›PMID 36853346›Full record

ArticleEuropean radiology2023

The role of ultrasound in screening subclinical psoriatic arthritis in patients with moderate to severe psoriasis.

Zi-Tong Chen, Rong-Fen Chen, Xiao-Long Li, Qiao Wang, Wei-Wei Ren, Dan-Dan Shan, Yu-Jing Zhao, Li-Ping Sun, Hui-Xiong Xu, Yu-Ling Shi and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Subclinical Enthesopathy in Psoriasis-An Ultrasonographic Study.Medical sciences (Basel, Switzerland) · 2024
    Observational
  5. Psoriasis as a Systemic Disease.Deutsches Arzteblatt international · 2024
    Review
  6. Review
  7. Imaging in psoriatic arthritis: established methods and emerging techniques.Therapeutic advances in musculoskeletal disease · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zi-Tong ChenDepartment of Medical Ultrasound, Shanghai Skin Disease Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai, China.
Rong-Fen ChenDepartment of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis, School of Medicine, Tongji University, Shanghai, 200443, China.
Xiao-Long LiDepartment of Ultrasound, Zhongshan Hospital, Institute of Ultrasound in Medicine and Engineering, Fudan University, Shanghai, 200032, China.
Qiao WangDepartment of Medical Ultrasound, Shanghai Skin Disease Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai, China.
Wei-Wei RenDepartment of Medical Ultrasound, Shanghai Skin Disease Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai, China.
Dan-Dan ShanDepartment of Medical Ultrasound, Shanghai Skin Disease Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai, China.
Yu-Jing ZhaoDepartment of Medical Imaging, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Li-Ping SunDepartment of Medical Ultrasound, Shanghai Skin Disease Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai, China.
Hui-Xiong XuDepartment of Ultrasound, Zhongshan Hospital, Institute of Ultrasound in Medicine and Engineering, Fudan University, Shanghai, 200032, China. xu.huixiong@zs-hospital.sh.cn.
Yu-Ling ShiDepartment of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis, School of Medicine, Tongji University, Shanghai, 200443, China. shiyuling1973@tongji.edu.cn.
Le-Hang GuoDepartment of Medical Ultrasound, Shanghai Skin Disease Hospital, Ultrasound Research and Education Institute, School of Medicine, Tongji University, Shanghai, China. gopp1314@hotmail.com.ORCID http://orcid.org/0000-0002-5685-1280
Tongji University · CNFudan University · CN

Funding

Clinical Research Plan of SHDC No. SHDC2020CR1014BClinical Research Plan of SHDC SHDC12018X06Fundamental Research Funds for the Central Universities 22120190213Innovation Program of Shanghai Municipal Education Commission No.2019-01-07-00-07-E00046National Natural Science Foundation of China 81872522National Natural Science Foundation of China 81901753National Natural Science Foundation of China 81927801National Natural Science Foundation of China 82001816National Natural Science Foundation of China 82072092National Natural Science Foundation of China 82073429Program of Shanghai Academic Research Leader No. 20XD1403300Science and Technology Commission of Shanghai Municipality 19441903200Science and Technology Commission of Shanghai Municipality 19DZ2251100Shanghai Municipal Health Commission 2019LJ21Shanghai Municipal Health Commission SHSLCZDZK03502
6 · The paper itself

Abstract

objectiveTo identify patients in the subclinical psoriatic arthritis (Sub-PsA) phase by ultrasound (US) and provide a solution to screen them.

methodsA total of 490 participants with moderate-to-severe psoriasis were evaluated. Among them, 384 participants without arthritis symptoms were enrolled into the silent psoriasis group and 106 participants with arthritis symptoms, called prodromal/active PsA phase, were enrolled into the clinical PsA group. Another 80 non-psoriasis participants were enrolled into the control group. Each participant received clinical assessments and US examinations of 60 joints, 38 tendons, and 40 entheses. We compared the incidences of synovio-enthesitis, synovitis, tenosynovitis, erosion, and dactylitis detected on US among the three groups. Subsequently, on the basis of significant US findings, we distinguished Sub-PsA from psoriasis alone (PsO) in the silent psoriasis group and analyzed the clinical characteristics, mainly including basic clinical characteristics, body surface area (BSA), and Psoriasis Area and Severity Index (PASI) score.

resultsOnly synovio-enthesitis significantly differed between the control group and the silent psoriasis group (1.3% vs. 16.1%, p < 0.001). The knee was the most commonly involved site of synovio-enthesitis (79.0%). Taking synovio-enthesitis as the standard, 16.1% of silent psoriasis participants and 12.7% of all psoriasis participants were in the Sub-PsA phase. Furthermore, there were no differences in BSA and PASI among the three phases of PsO, Sub-PsA, and prodromal/active PsA.

conclusionsSince the psoriasis patients in Sub-PsA phase was as high as 12.7% in all patients with moderate-to-severe psoriasis, US-detected synovio-enthesitis was recommended routinely for screening them regardless of arthritis symptoms, especially in the lower limbs. KEY POINTS: • Synovio-enthesitis on ultrasound was significantly associated with subclinical psoriatic arthritis, especially in the lower limbs. • Routine ultrasound evaluation could help screen psoriasis patients in the subclinical psoriatic arthritis phase, which was as high as 12.7% in all psoriasis patients.

Indexed as

Arthritis, PsoriaticEnthesopathyPsoriasisTenosynovitisHumansSeverity of Illness IndexUltrasonographyPsoriasisPsoriatic arthritisUltrasound

Identifiers

PMID36853346
OpenAlexW4322617190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.