Evidence map›Paper›PMID 36853190›Full record

ArticleACS infectious diseases2023

7-

William Nguyen, Madeline G Dans, Iain Currie, Jon Kyle Awalt, Brodie L Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh and 16 more

Open access · bronzeAbstract read
In one paragraph

Article in ACS infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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  14. Analysis ofBio-protocol · 2023
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 10 institutions in 5 countries.

William NguyenThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Madeline G DansThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Iain CurrieThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Jon Kyle AwaltThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.ORCID 0000-0003-4840-2757
Brodie L BaileyThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Chris LumbThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Anna NgoThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Paola FavuzzaThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Josephine PalandriThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Saishyam RameshResearch School of Biology, The Australian National University, Canberra 2600, Australia.
Jocelyn PeningtonThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.ORCID 0000-0003-1561-0074
Kate E JarmanThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Partha MukherjeeTCG Lifesciences, Kolkata, West Bengal 700091, India.
Arnish ChakrabortyTCG Lifesciences, Kolkata, West Bengal 700091, India.
Alexander G MaierResearch School of Biology, The Australian National University, Canberra 2600, Australia.
Giel G van DoorenResearch School of Biology, The Australian National University, Canberra 2600, Australia.
Tony PapenfussThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Sergio WittlinSwiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland.ORCID 0000-0002-0811-0912
Alisje ChurchyardDepartment of Life Sciences, Imperial College London, South Kensington, SW7 2AZ U.K.
Jake BaumDepartment of Life Sciences, Imperial College London, South Kensington, SW7 2AZ U.K.
Elizabeth A WinzelerSchool of Medicine, University of California San Diego, 9500 Gilman Drive 0760, La Jolla, California 92093, United States.ORCID 0000-0002-4049-2113
Delphine BaudMedicines for Malaria Venture, Geneva 1215, Switzerland.
Stephen BrandMedicines for Malaria Venture, Geneva 1215, Switzerland.
Paul F JacksonGlobal Public Health, Janssen R&D LLC, La Jolla, California 92121, United States.
Alan F CowmanThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
Brad E SleebsThe Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.ORCID 0000-0001-9117-1048
The University of Melbourne · AUAustralian National University · AUMedicines for Malaria Venture · CHTCG Lifesciences (India) · INWalter and Eliza Hall Institute of Medical Research · AUImperial College London · GBJanssen (United States) · USSwiss Tropical and Public Health Institute · CHUniversity of California San Diego · USUNSW Sydney · AU

Funding

Wellcome Trust
6 · The paper itself

Abstract

The development of new antimalarials is required because of the threat of resistance to current antimalarial therapies. To discover new antimalarial chemotypes, we screened the Janssen Jumpstarter library against the

Indexed as

AntimalarialsFolic Acid AntagonistsMalaria, FalciparumQuinolonesAnimalsCytochromes bMicePlasmodium falciparumAntimalarialsCytochromes bFolic Acid AntagonistsQuinolonesantimalarialcytochrome bc1malariamitochondriaPlasmodium

Identifiers

PMID36853190
PMCPMC10012268
OpenAlexW4322617069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.