Evidence map›Paper›PMID 36853005›Full record

ArticleInfection and immunity2023

Endogenous Linear Plasmids lp28-4 and lp25 Are Required for Infectivity and Restriction Protection in the Lyme Disease Spirochete Borrelia mayonii.

Timothy Casselli, Yvonne Tourand, Kaitlyn Gura, Brian Stevenson, Wolfram R Zückert, Catherine A Brissette

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Frontiers in immunology · 2026
    Article
  2. Silent Spread ofHealthcare (Basel, Switzerland) · 2025
    Article
  3. Virulence Regulation inMicroorganisms · 2025
    Review
  4. Pathogens (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Timothy Casselli *Department of Biological Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA.ORCID 0000-0003-1954-2443
Yvonne Tourand *Department of Biological Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA.ORCID 0000-0002-4751-6683
Kaitlyn GuraDepartment of Biological Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA.
Brian StevensonDepartment of Microbiology, Immunology, and Molecular Genetics, School of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0002-2406-4776
Wolfram R ZückertDepartment of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0002-7350-2162
Catherine A BrissetteDepartment of Biological Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA.ORCID 0000-0003-0792-1403
University of North Dakota · USUniversity of Kansas Medical Center · USUniversity of Kentucky · US

Funding

The role of class IIa Hdac in regulating cell fate choice in early cortical development.P20GM104360 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI ROCHE, BENJAMIN · 2013 to 2023
$21.1M
Tracking and Evaluation CoreU54GM128729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BASSON, MARC D. · 2018 to 2022
$20.3M
Yersina perstis interactions with macrophagesP20GM113123 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI COMBS, COLIN K · 2016 to 2025
$19.9M
Pathogenesis of Borrelia mayonii infectionR21AI129522 · NIAID · UNIVERSITY OF KENTUCKY · PI STEVENSON, BRIAN · 2017 to 2018
$433k
NIAID NIH HHS R21 AI129522NIGMS NIH HHS P20 GM104360NIGMS NIH HHS P20 GM113123NIGMS NIH HHS U54 GM128729
6 · The paper itself

Abstract

Borrelia mayonii is a newly recognized causative agent of Lyme disease in the Upper Midwestern United States, with distinct clinical presentations compared to classical Lyme disease caused by other Lyme

Indexed as

Borrelia burgdorferiBorrelia burgdorferi GroupLyme DiseaseAnimalsMammalsMiceMice, Inbred C3HPlasmidsSpirochaetalesBorrelia mayoniiinfectionLyme diseaseplasmidsrestriction modification systemsvirulence determinants

Identifiers

PMID36853005
PMCPMC10016076
OpenAlexW4322617238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.