ArticleeLife2023
Prolonged partner separation erodes nucleus accumbens transcriptional signatures of pair bonding in male prairie voles.
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 27 citations in OpenAlex.
- On the nature of grief: uncovering the evolutionary roots of loss across the animal realm.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding.bioRxiv : the preprint server for biology · 2026Article
- Accumbal calcium-permeable AMPA receptors orchestrate neuronal ensembles underlying social attachment.Nature communications · 2026Article
- Social isolation, but not partner separation, lowers hippocampal synaptosome mitochondrial respiration in female California mice (Peromyscus californicus).Psychoneuroendocrinology · 2025Article
- Mapping the cellular basis of species differences in oxytocin and dopamine receptor expression in the vole nucleus accumbens.Scientific reports · 2025Article
- Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation.Research square · 2025Article
- Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation.bioRxiv : the preprint server for biology · 2025Article
- Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage.Frontiers in genome editing · 2025Article
- Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships.bioRxiv : the preprint server for biology · 2024Article
- Aging leads to sex-dependent effects on pair bonding and increased number of oxytocin-producing neurons in monogamous prairie voles.Hormones and behavior · 2024Article
- Opto2P-FCM: A MEMS based miniature two-photon microscope with two-photon patterned optogenetic stimulation.bioRxiv : the preprint server for biology · 2024Article
- Cholinergic interneurons in the nucleus accumbens are a site of cellular convergence for corticotropin-releasing factor and estrogen regulation in male and female mice.The European journal of neuroscience · 2024Article
- Prairie voles as a model for adaptive reward remodeling following loss of a bonded partner.Annals of the New York Academy of Sciences · 2024Review
- Neurobiology and treatment advances for prolonged grief disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Attachment across the lifespan: Examining the intersection of pair bonding neurobiology and healthy aging.Neuroscience and biobehavioral reviews · 2023Review
- Recovering from a broken heart.eLife · 2023Article
- Prairie vole pair bonding and plasticity of the social brain.Trends in neurosciences · 2023Article
- Partner separation rescues pair bond-induced decreases in hypothalamic oxytocin neural densities.Scientific reports · 2023Article
- Article
- Social experience alters oxytocinergic modulation in the nucleus accumbens of female prairie voles.Current biology : CB · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The loss of a spouse is often cited as the most traumatic event in a person's life. However, for most people, the severity of grief and its maladaptive effects subside over time via an understudied adaptive process. Like humans, socially monogamous prairie voles (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.