ArticleAnimal models and experimental medicine2023
Era of the 4D animal model.
Article in Animal models and experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- ND-AMD: A Web-Based Database for Animal Models of Neurological Disease With Analysis Tools.CNS neuroscience & therapeutics · 2025Article
- Flu-CED: A comparative transcriptomics database of influenza virus-infected human and animal models.Animal models and experimental medicine · 2024Article
- Era of the 4D animal model.Animal models and experimental medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Revealing the entire dynamics of pathogenesis is critical for understanding, preventing and treating human disease but is limited by systematic clinical sampling. This drawback can be overcome with animal model studies. Recent advances in phenotyping, omics and bioinformatics technologies promote the development of the 4D animal model to simulate and digitally display the spatiotemporal landscapes of phenotypes and molecular dynamics in human diseases and reveal novel targets for diagnosis and therapy. In this commentary, the origin, supporting technologies, content, function and application, and advantages of 4D animal models over clinical studies and traditional animal models, as well as their limitations, are presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.