Evidence map›Paper›PMID 36852480›Full record

ArticleeLife2023

A parasitic fungus employs mutated eIF4A to survive on rocaglate-synthesizing

Mingming Chen, Naoyoshi Kumakura, Hironori Saito, Ryan Muller, Madoka Nishimoto, Mari Mito, Pamela Gan, Nicholas T Ingolia, Ken Shirasu, Takuhiro Ito and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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  6. Mettl1-dependent mNature communications · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Mingming Chen *Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.ORCID 0000-0003-4453-1105
Naoyoshi Kumakura *Plant Immunity Research Group, RIKEN Center for Sustainable Resource Science, Yokohama, Japan.ORCID 0000-0003-0259-2444
Hironori SaitoDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.ORCID 0000-0001-9623-4132
Ryan MullerDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-8868-7841
Madoka NishimotoLaboratory for Translation Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan.ORCID 0000-0003-0948-2504
Mari MitoRNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Japan.ORCID 0000-0003-2564-6273
Pamela GanPlant Immunity Research Group, RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
Nicholas T IngoliaDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-3395-1545
Ken ShirasuPlant Immunity Research Group, RIKEN Center for Sustainable Resource Science, Yokohama, Japan.ORCID 0000-0002-0349-3870
Takuhiro ItoLaboratory for Translation Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan.ORCID 0000-0003-3704-5205
Yuichi ShichinoRNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Japan.ORCID 0000-0002-0093-1185
Shintaro IwasakiDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.ORCID 0000-0001-7724-3754
Pioneer (United States) · USRIKEN Center for Sustainable Resource Science · JPRIKEN Center for Biosystems Dynamics Research · JPUniversity of California, Berkeley · US

Funding

Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
NIH HHS S10 OD018174
6 · The paper itself

Abstract

Plants often generate secondary metabolites as defense mechanisms against parasites. Although some fungi may potentially overcome the barrier presented by antimicrobial compounds, only a limited number of examples and molecular mechanisms of resistance have been reported. Here, we found an

Indexed as

AglaiaHypocrealesParasitesAmino Acid SubstitutionAnimalsMutationAglaiabiochemistrychemical biologyColletotrichum orbiculareecologyeIF4AOphiocordycepstranslationtranslation inhibitor

Identifiers

PMID36852480
PMCPMC9977294
OpenAlexW4322488384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.