Evidence map›Paper›PMID 36852460›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

LncRNA XLOC_015548 affects the proliferation and differentiation of myoblasts via the MAPK signaling pathway.

Yihao Wei, Tiantian Qi, Siyang Cao, Weifei Zhang, Fei Yu, Hui Zeng, Jian Weng

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cloning of the RNA mVeterinary sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yihao WeiDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.ORCID 0000-0002-7636-0294
Tiantian QiDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Siyang CaoDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Weifei ZhangDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Fei YuDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Hui ZengDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Jian WengDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, an increasing number of studies have reported that long non-coding RNAs (lncRNAs) play essential regulatory roles in myogenic differentiation. In this study, a specific LncRNA XLOC_015548 (Lnc000280) was identified. However, little research has explored its mechanism of action by constructing XLOC_015548 gene editing cell models. In this study, relevant sequences were obtained according to the RNA-seq results. Subsequently, XLOC_015548 knockdown and over-expression lentiviral vectors were constructed, and the C2C12 myoblast cell line was transfected to prepare the XLOC_015548 gene-edited myoblast model. The

Indexed as

MAP Kinase Signaling SystemRNA, Long NoncodingCell DifferentiationCell ProliferationMyoblastsMyogeninSignal TransductionMyogeninRNA, Long NoncodingLong non-coding RNA XLOC_015548MAPK signaling pathwaymusclemyoblast differentiationmyogenesisRNA sequencing

Identifiers

PMID36852460
PMCPMC10281533

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.