Evidence map›Paper›PMID 36852457›Full record

ArticleGut microbes

Effect of food additives on key bacterial taxa and the mucosa-associated microbiota in Crohn's disease. The ENIGMA study.

J J Jimenez Loayza, S Kang, L Schooth, J J Teh, A de Klerk, E K Noon, J Zhang, J Hu, A L Hamilton, A Wilson-O'Brien and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

J J Jimenez LoayzaFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.
S KangFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.
L SchoothFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.
J J TehFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.
A de KlerkFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.
E K NoonFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.
J ZhangDepartment of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China.
J HuDepartment of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China.
A L HamiltonDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Australia.
A Wilson-O'BrienDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Australia.
G L TrakmanDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Australia.
W LinMicrobiota I-Center (Magic), Hong Kong, China.
J ChingDepartment of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China.
L OrDepartment of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China.
J J Y SungLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
J YuDepartment of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China.
S C NgDepartment of Medicine and Therapeutics, the Chinese University of Hong Kong, Hong Kong, China.
M A KammDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Australia.
M MorrisonFrazer Institute, Faculty of Medicine, University of Queensland, Brisbane, Australia.ORCID 0000-0001-9257-9133
The University of Queensland · AUChinese University of Hong Kong · HKThe University of Melbourne · AUNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food additives have been linked to the pro-inflammatory microbial dysbiosis associated with Crohn's disease (CD) but the underlying ecological dynamics are unknown. Here, we examine how selection of food additives affects the growth of multiple strains of a key beneficial bacterium (

Indexed as

Crohn DiseaseGastrointestinal MicrobiomeMicrobiotaBacteriaCarboxymethylcellulose SodiumCarrageenanFood AdditivesHumansPolysorbatesRNA, Ribosomal, 16SSaccharinSulfitesCarboxymethylcellulose SodiumCarrageenanFood AdditivesPolysorbatesRNA, Ribosomal, 16SSaccharinsodium sulfiteSulfitesFaecalibacterium prausnitziifood additivesGut microbiotainflammatory bowel diseaseProteusVeillonella

Identifiers

PMID36852457
PMCPMC9980662
OpenAlexW4322616767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.