Evidence map›Paper›PMID 36852272›Full record

ArticleiScience2023

Apolipoprotein H induces sex-specific steatohepatitis and gut dysbiosis during chronic hepatitis B infection.

Yaming Liu, Yangtao Wu, Xiaoming Jiang, Bo Chen, Jing Lu, Zexin Cai, Baorong Fu, Wei Zheng, Ruihong Wu, Gang Chen and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Occult hepatitis B in blood donation centers.Journal of medicine and life · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yaming LiuDepartment of Gastroenterology and Hepatology, Xiamen University Zhongshan Hospital, Xiamen, Fujian Province 361001, China.
Yangtao WuDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, Fujian Province 361001, China.
Xiaoming JiangDepartment of Hepatology, The First Hospital of Jilin University, Changchun, Jilin Province 132001, China.
Bo ChenDepartment of Hepatobiliary Surgery, The first affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, China.
Jing LuDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, Fujian Province 361001, China.
Zexin CaiDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, Fujian Province 361001, China.
Baorong FuDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, Fujian Province 361001, China.
Wei ZhengDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, Fujian Province 361001, China.
Ruihong WuDepartment of Hepatology, The First Hospital of Jilin University, Changchun, Jilin Province 132001, China.
Gang ChenDepartment of Hepatobiliary Surgery, The first affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, China.
Shulan TianDivision of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Jianlin RenDepartment of Gastroenterology and Hepatology, Xiamen University Zhongshan Hospital, Xiamen, Fujian Province 361001, China.
Xiamen University · CNJilin University · CNWenzhou Medical University · CNMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apolipoprotein H (APOH) is involved in lipid metabolism and functions as an acute-phase protein during hepatitis B virus (HBV) infection. Herein, we explored whether APOH acts on the development of fatty liver upon chronic HBV infection. Serum APOH level was significantly lower in cirrhosis patients than in healthy controls or patients with chronic infection. It showed sex bias, with elevated levels in female patients with chronic infection. Also, serum APOH levels were negatively correlated with HBV surface antigen (HBsAg) but positively correlated with albumin and triglyceride levels. In

Indexed as

Human metabolismMicrobiomeVirology

Identifiers

PMID36852272
PMCPMC9958358
OpenAlexW4318822299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.