Evidence map›Paper›PMID 36852267›Full record

ArticleOpen medicine (Warsaw, Poland)2023

UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling.

Ping Zhang, Huiping Guo, Fang Zhao, Ke Jia, Fei Yang, Xiaoli Liu

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Ubiquitin-conjugating Enzymes in Cancer.International journal of biological sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The role of ubiquitin-conjugating enzyme in the process of spermatogenesis.Reproductive biology and endocrinology : RB&E · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ping ZhangDepartment of Gynaecology, The First People's Hospital of Zhangjiagang Affiliated to Suzhou University, No. 68, West Jiyang Road, Zhangjiagang 215600, Jiangsu, China.
Huiping GuoDepartment of Gynaecology, The First People's Hospital of Zhangjiagang Affiliated to Suzhou University, Zhangjiagang 215600, Jiangsu, China.
Fang ZhaoDepartment of Gynaecology, The First People's Hospital of Zhangjiagang Affiliated to Suzhou University, Zhangjiagang 215600, Jiangsu, China.
Ke JiaDepartment of Gynaecology, The First People's Hospital of Zhangjiagang Affiliated to Suzhou University, Zhangjiagang 215600, Jiangsu, China.
Fei YangDepartment of Gynaecology, The First People's Hospital of Zhangjiagang Affiliated to Suzhou University, Zhangjiagang 215600, Jiangsu, China.
Xiaoli LiuDepartment of Gynaecology, The First People's Hospital of Zhangjiagang Affiliated to Suzhou University, Zhangjiagang 215600, Jiangsu, China.
Soochow University · CNZhangjiagang First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence has demonstrated that ubiquitin conjugating enzyme E2 J1 (UBE2J1) exerts pivotal function in many cancers. UBE2J1 was reported to be dysregulated in endometrial cancer (EC). This study was designed to further investigate the regulatory character and mechanism of UBE2J1 in EC. Bioinformatic tools and databases were used to analyze gene expression pattern and gene expression correlation in EC tissues, and the prognosis of EC patients. Gene expression was evaluated by reverse-transcription quantitative polymerase chain reaction. Western blot was used for protein level detection.

Indexed as

cell apoptosisendometrial cancerMDM2/p53 pathwayPI3K/AKT pathwayUBE2J1

Identifiers

PMID36852267
PMCPMC9961967
OpenAlexW4321844963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.