Evidence map›Paper›PMID 36852226›Full record

ArticleMaterials today. Bio2023

Nanocellulose composite wound dressings for real-time pH wound monitoring.

Olof Eskilson, Elisa Zattarin, Linn Berglund, Kristiina Oksman, Kristina Hanna, Jonathan Rakar, Petter Sivlér, Mårten Skog, Ivana Rinklake, Rozalin Shamasha and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 94 citations in OpenAlex.

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  19. Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Olof EskilsonLaboratory of Molecular Materials, Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology, Linköping University, SE-581 83, Linköping, Sweden.
Elisa ZattarinLaboratory of Molecular Materials, Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology, Linköping University, SE-581 83, Linköping, Sweden.
Linn BerglundDivision of Materials Science, Department of Engineering Sciences and Mathematics, Luleå University of Technology, SE-971 87, Luleå, Sweden.
Kristiina OksmanDivision of Materials Science, Department of Engineering Sciences and Mathematics, Luleå University of Technology, SE-971 87, Luleå, Sweden.
Kristina HannaCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Jonathan RakarCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Petter SivlérLaboratory of Molecular Materials, Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology, Linköping University, SE-581 83, Linköping, Sweden.
Mårten SkogLaboratory of Molecular Materials, Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology, Linköping University, SE-581 83, Linköping, Sweden.
Ivana RinklakeCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Rozalin ShamashaCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Zeljana SotraCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Annika StarkenbergCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Magnus OdénDivision of Nanostructured Materials, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-58183, Linköping, Sweden.
Emanuel WimanCardiovascular Research Centre, School of Medical Sciences, Örebro University, SE-70362, Örebro, Sweden.
Hazem KhalafCardiovascular Research Centre, School of Medical Sciences, Örebro University, SE-70362, Örebro, Sweden.
Torbjörn BengtssonCardiovascular Research Centre, School of Medical Sciences, Örebro University, SE-70362, Örebro, Sweden.
Johan P E JunkerCenter for Disaster Medicine and Traumatology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
Robert SelegårdLaboratory of Molecular Materials, Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology, Linköping University, SE-581 83, Linköping, Sweden.
Emma M BjörkDivision of Nanostructured Materials, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-58183, Linköping, Sweden.
Daniel AiliLaboratory of Molecular Materials, Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology, Linköping University, SE-581 83, Linköping, Sweden.
Linköping University · SEÖrebro University · SELuleå University of Technology · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is the largest organ of the human body. Wounds disrupt the functions of the skin and can have catastrophic consequences for an individual resulting in significant morbidity and mortality. Wound infections are common and can substantially delay healing and can result in non-healing wounds and sepsis. Early diagnosis and treatment of infection reduce risk of complications and support wound healing. Methods for monitoring of wound pH can facilitate early detection of infection. Here we show a novel strategy for integrating pH sensing capabilities in state-of-the-art hydrogel-based wound dressings fabricated from bacterial nanocellulose (BC). A high surface area material was developed by self-assembly of mesoporous silica nanoparticles (MSNs) in BC. By encapsulating a pH-responsive dye in the MSNs, wound dressings for continuous pH sensing with spatiotemporal resolution were developed. The pH responsive BC-based nanocomposites demonstrated excellent wound dressing properties, with respect to conformability, mechanical properties, and water vapor transmission rate. In addition to facilitating rapid colorimetric assessment of wound pH, this strategy for generating functional BC-MSN nanocomposites can be further be adapted for encapsulation and release of bioactive compounds for treatment of hard-to-heal wounds, enabling development of novel wound care materials.

Indexed as

Bacterial nanocelluloseInfectionMesoporous silica nanoparticlespH sensorWound dressing

Identifiers

PMID36852226
PMCPMC9958357
OpenAlexW4319303244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.