Evidence map›Paper›PMID 36851978›Full record

ArticleMethodsX2023

Fast-screening flow cytometry method for detecting nanoplastics in human peripheral blood.

Roser Salvia, Laura G Rico, Jolene A Bradford, Michael D Ward, Michael W Olszowy, Cristina Martínez, Álvaro Domingo Madrid-Aris, Joan R Grífols, Águeda Ancochea, Laia Gomez-Muñoz and 5 more

Open access · goldAbstract read
In one paragraph

Article in MethodsX, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  8. Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review.Journal of exposure science & environmental epidemiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Roser SalviaGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Laura G RicoGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Jolene A BradfordThermo Fisher Scientific, Eugene, Oregon, United States.
Michael D WardThermo Fisher Scientific, Eugene, Oregon, United States.
Michael W OlszowySartorius Stedim North America, inc., Arvada, Colorado, United States.
Cristina MartínezLleida Biomedical Research Institute's Dr. Pifarré Foundation (IRBLleida), Lleida, Spain.
Álvaro Domingo Madrid-ArisSant Joan de Deu Research Institute (SJD), Esplugues de Llobregat, Barcelona, Spain.
Joan R GrífolsBanc de Sang i Teixits (BST), Barcelona, Spain.
Águeda AncocheaBanc de Sang i Teixits (BST), Barcelona, Spain.
Laia Gomez-MuñozGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Marta Vives-PiGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Eva Martínez-CáceresGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Marco A FernándezGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Marc SorigueGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Jordi PetrizGermans Trias i Pujol Research Institute (IGTP), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona, Barcelona, Spain.
Universitat Autònoma de Barcelona · ESBanc de Sang i Teixits · ESThermo Fisher Scientific (United States) · USBiomedical Research Institute of Lleida · ESSant Joan de Déu Research Foundation · ESSartorius (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plastic pollution is a global problem. Animals and humans can ingest and inhale plastic particles, with uncertain health consequences. Nanoplastics (NPs) are particles ranging from 1 nm to 1000 nm that result from the erosion or breakage of larger plastic debris, and can be highly polydisperse in physical properties and heterogeneous in composition. Potential effects of NPs exposure may be associated with alterations in the xenobiotic metabolism, nutrients absorption, energy metabolism, cytotoxicity, and behavior. In humans, no data on NPs absorptions has been reported previously. Given that their detection relies significantly on environmental exposure, we have prospectively studied the presence of NPs in human peripheral blood (PB). Specifically, we have used fluorescence techniques and nanocytometry, together with the staining of the lipophilic dye Nile Red (NR), to demonstrate that NPs can be accurately detected using flow cytometry.•Potential effects of nanoplastics exposure.•Fluorescence techniques and nanocytometry.•Accurate detection using flow cytometry.

Indexed as

BloodFlow cytometryLive Cell ImagingNanocytometryNanoplasticsNile RedPlastic pollution

Identifiers

PMID36851978
PMCPMC9958479
OpenAlexW4319790010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.