Evidence map›Paper›PMID 36851738›Full record

ArticleViruses2023

Prediction of Specific Antibody- and Cell-Mediated Responses Using Baseline Immune Status Parameters of Individuals Received Measles-Mumps-Rubella Vaccine.

Anna Toptygina, Dmitry Grebennikov, Gennady Bocharov

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Anna ToptyginaGabrichevsky Research Institute for Epidemiology and Microbiology, 125212 Moscow, Russia.ORCID 0000-0002-9981-4762
Dmitry GrebennikovMarchuk Institute of Numerical Mathematics, Russian Academy of Sciences, (INM RAS), 119333 Moscow, Russia.ORCID 0000-0002-7315-193X
Gennady BocharovMarchuk Institute of Numerical Mathematics, Russian Academy of Sciences, (INM RAS), 119333 Moscow, Russia.ORCID 0000-0002-5049-0656
Russian Academy of Sciences · RUGabrichevsky Institute of Epidemiology and Microbiology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A successful vaccination implies the induction of effective specific immune responses. We intend to find biomarkers among various immune cell subpopulations, cytokines and antibodies that could be used to predict the levels of specific antibody- and cell-mediated responses after measles-mumps-rubella vaccination. We measured 59 baseline immune status parameters (frequencies of 42 immune cell subsets, levels of 13 cytokines, immunoglobulins) before vaccination and 13 response variables (specific IgA and IgG, antigen-induced IFN-γ production, CD107a expression on CD8+ T lymphocytes, and cellular proliferation levels by CFSE dilution) 6 weeks after vaccination for 19 individuals. Statistically significant Spearman correlations between some baseline parameters and response variables were found for each response variable (

Indexed as

MeaslesMumpsRubellaAntibodiesCytokinesHumansMeasles-Mumps-Rubella VaccineAntibodiesCytokinesMeasles-Mumps-Rubella Vaccineantibody-mediated responsecell-mediated responsecorrelation analysismeasles–mumps–rubellamultivariable linear regressionpost-vaccination immune responsepredictors

Identifiers

PMID36851738
PMCPMC9960117
OpenAlexW4320730363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.