Evidence map›Paper›PMID 36851735›Full record

ArticleViruses2023

Persistence of a Frameshifting Deletion in SARS-CoV-2 ORF7a for the Duration of a Major Outbreak.

Charles S P Foster, Rowena A Bull, Nicodemus Tedla, Fernando Santiago, David Agapiou, Anurag Adhikari, Gregory J Walker, Lok Bahadur Shrestha, Sebastiaan J Van Hal, Ki Wook Kim and 1 more

Abstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Charles S P FosterSerology and Virology Division (SAViD), NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW 2031, Australia.ORCID 0000-0002-6700-3746
Rowena A BullSchool of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-9844-3744
Nicodemus TedlaSchool of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia.
Fernando SantiagoSchool of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia.
David AgapiouThe Kirby Institute for Infection and Immunity, University of New South Wales, Sydney, NSW 2052, Australia.
Anurag AdhikariSchool of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia.
Gregory J WalkerSerology and Virology Division (SAViD), NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW 2031, Australia.ORCID 0000-0003-0044-1394
Lok Bahadur ShresthaSchool of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-0054-0715
Sebastiaan J Van HalDepartment of Infectious Diseases and Microbiology, NSW Health Pathology, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia.
Ki Wook KimSerology and Virology Division (SAViD), NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW 2031, Australia.ORCID 0000-0001-9579-6408
William D RawlinsonSerology and Virology Division (SAViD), NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW 2031, Australia.ORCID 0000-0003-0988-7827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Australia experienced widespread COVID-19 outbreaks from infection with the SARS-CoV-2 Delta variant between June 2021 and February 2022. A 17-nucleotide frameshift-inducing deletion in ORF7a rapidly became represented at the consensus level (Delta-ORF7a

Indexed as

COVID-19SARS-CoV-2AustraliaDisease OutbreaksHumansPandemicsRetrospective StudiesViral ProteinsORF7a protein, SARS-CoV-2Viral ProteinsindelORF7aoutbreakSARS-CoV-2

Identifiers

PMID36851735
PMCPMC9966144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.