Evidence map›Paper›PMID 36851718›Full record

ArticleViruses2023

Transcriptional Reprogramming of Autographa Californica Multiple Nucleopolyhedrovirus Chitinase and Cathepsin Genes Enhances Virulence.

Jeffrey J Hodgson, A Lorena Passarelli, Peter J Krell

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. An overview of viral chitinases: General properties and biotechnological potential.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jeffrey J HodgsonDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0003-1484-6544
A Lorena PassarelliDivision of Biology, Kansas State University, Manhattan, KS 66502, USA.ORCID 0000-0001-8103-5915
Peter J KrellDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-1149-5382
Kansas State University · USUniversity of Guelph · CA

Funding

Arbovirus midgut escape mechanismsR01AI091972 · NIAID · KANSAS STATE UNIVERSITY · PI FRANZ, ALEXANDER W E, PASSARELLI, A. LORENA · 2012 to 2015
$2.6M
NIAID NIH HHS R01 AI091972
6 · The paper itself

Abstract

The baculoviral chitinase (CHIA) and cathepsin (V-CATH) enzymes promote terminal insect host liquefaction, which aids viral progeny dissemination. Recombinant Autographa californica nucleopolyhedrovirus (AcMNPV)-derived viruses were previously generated with reprogrammed

Indexed as

ChitinasesAnimalsBaculoviridaeCathepsinsLarvaNucleopolyhedrovirusesSpodopteraTranscription, GeneticVirulenceCathepsinsChitinasesbaculovirusbiopesticidecathepsinchitinaseenzymes

Identifiers

PMID36851718
PMCPMC9965964
OpenAlexW4320492825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.