Evidence map›Paper›PMID 36851687›Full record

ArticleViruses2023

HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit.

Danni Jin, Yiping Zhu, Heidi L Schubert, Stephen P Goff, Karin Musier-Forsyth

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Danni JinDepartment of Chemistry and Biochemistry, Center for Retrovirus Research, Center for RNA Biology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-2878-9950
Yiping ZhuDepartments of Biochemistry and Molecular Biophysics, and Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA.
Heidi L SchubertDepartment of Biochemistry, University of Utah, Salt Lake City, UT 841122, USA.
Stephen P GoffDepartments of Biochemistry and Molecular Biophysics, and Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA.ORCID 0000-0002-9679-0582
Karin Musier-ForsythDepartment of Chemistry and Biochemistry, Center for Retrovirus Research, Center for RNA Biology, Ohio State University, Columbus, OH 43210, USA.
Columbia University Irving Medical Center · USThe Ohio State University · USUniversity of Utah · US

Funding

CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral DynamicsU54AI170856 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI WALTHER H MOTHES · 2022 to 2026
$34.4M
Center for Structural Biology of HIV RNAU54AI170660 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALICE TELESNITSKY · 2022 to 2026
$32.1M
RNA binding and packaging by retroviral Gag proteinsR01AI153216 · NIAID · OHIO STATE UNIVERSITY · PI MUSIER-FORSYTH, KARIN M · 2020 to 2025
$4.9M
Mechanisms of Silencing of Retroviral DNAs in Embryonic Cell LinesR01CA030488 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GOFF, STEPHEN PAINE · 1985 to 2024
$4.3M
Cellular Factors Critical for Initiation of HIV-1 Reverse TranscriptaseR01AI150493 · NIAID · OHIO STATE UNIVERSITY · PI MUSIER-FORSYTH, KARIN M · 2020 to 2022
$1.2M
NCI NIH HHS R01 CA030488NIAID NIH HHS R01 AI150493NIAID NIH HHS R01 AI153216NIAID NIH HHS U54 AI170660NIAID NIH HHS U54 AI170856NIH HHS RO1 AI150493NIH HHS RO1 AI153216NIH HHS RO1 CA030488NIH HHS U54 AI170660NIH HHS U54 AI170856
6 · The paper itself

Abstract

Host factor tRNAs facilitate the replication of retroviruses such as human immunodeficiency virus type 1 (HIV-1). HIV-1 uses human tRNA

Indexed as

Amino Acyl-tRNA SynthetasesHIV-1CytoplasmCytosolHumansProtein SubunitsProteomicsAmino Acyl-tRNA Synthetasesglutamyl-prolyl-tRNA synthetaseProtein Subunitsglutamyl-prolyl tRNA synthetaseHIV-1 MA–tRNA interactionsHIV-dependency factorshuman immunodeficiency virus type 1multi-aminoacyl-tRNA synthetase complex

Identifiers

PMID36851687
PMCPMC9967848
OpenAlexW4319759263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.