Evidence map›Paper›PMID 36851604›Full record

ArticleViruses2023

Antiviral Effect of Manganese against Foot-and-Mouth Disease Virus Both in PK15 Cells and Mice.

Zhixiong Zhang, Rui Zhang, Juanbin Yin, Shuaiyang Zhao, Xiaodong Qin, Fei Chen, Yang Yang, Ling Bai, Zijing Guo, Yongshu Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. MnVeterinary sciences · 2026
    Article
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  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Zhixiong ZhangState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Rui ZhangCollege of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China.
Juanbin YinState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Shuaiyang ZhaoState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Xiaodong QinState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Fei ChenState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Yang YangState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Ling BaiState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Zijing GuoCollege of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China.ORCID 0000-0002-2291-700X
Yongshu WuState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China.
Yanmin LiCollege of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China.
Zhidong ZhangCollege of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China.ORCID 0000-0002-2186-7661
Lanzhou Veterinary Research Institute · CNUnited States Department of State · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foot-and-mouth disease (FMD) is an acute contagious disease of cloven-hoofed animals such as cattle, pigs, and sheep. Current emergency FMD vaccines are of limited use for early protection because their protective effect starts 7 days after vaccination. Therefore, antiviral drugs or additives are used to rapidly stop the spread of the virus during FMD outbreaks. Manganese (Mn

Indexed as

Antiviral AgentsFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusManganeseAnimalsCattleCell LineInterferonsMiceMice, Inbred C57BLSheepSwineAntiviral AgentsInterferonsManganeseantiviral effectcytokinesfoot-and-mouth disease virusMn2+

Identifiers

PMID36851604
PMCPMC9964130
OpenAlexW4318480585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.